Save up -80% on Interferon beta-1b

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Interferon beta-1b

Extavia 0.3 mg kit

$196.76

kit

* price without discount in nearest pharmacy. Price may vary.

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Interferon beta-1b volume of distribution

* 0.25 to 2,88 L/kg

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What is Interferon beta-1b

Human interferon beta (165 residues), cysteine 17 is substituted with serine. Produced in E. coli, no carbohydrates, MW=18.5kD

Interferon beta-1b mechanism of action

Interferon beta binds to type I interferon receptors (IFNAR1 and IFNAR2c) which activate two Jak (Janus kinase) tyrosine kinases (Jak1 and Tyk2). These transphosphorylate themselves and phosphorylate the receptors. The phosphorylated INFAR receptors then bind to Stat1 and Stat2 (signal transducers and activators of transcription)which dimerize and activate multiple (~100) immunomodulatory and antiviral proteins. Interferon beta binds more stably to type I interferon receptors than interferon alpha.

Dosage forms of Interferon beta-1b

FormRouteStrength
Powder and solvent for solution for injectionSubcutaneous use0.25 mg/ml
Prescription Generics

false

International Brands

Betaseron

Synonyms

Fibroblast interferon IFN-beta

Manufacturers

Bayer Health Care Pharmaceuticals Inc.

CAS number

145155-23-3

UNII

TTD90R31WZ

State

liquid

Affected organisms

Humans and other mammals

Indication of Interferon beta-1b

Interferon beta-1b is a drug used for the treatment of relapsing/remitting multiple sclerosis. It has been shown to slow the advance of the disease as well as to decrease the frequency of attacks.

Toxicity of Interferon beta-1b

RX24 Drugs Disclaimer: before buying a Interferon beta-1b on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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