Save up -80% on Iohexol

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Iohexol

Omnipaque 300 mg/ml syringe

$1.08

ml

* price without discount in nearest pharmacy. Price may vary.

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Iohexol volume of distribution

* 350-849 mL/kg

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What is Iohexol

Iohexol is an effective non-ionic, water-soluble contrast agent which is used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures. Its low systemic toxicity is the combined result of low chemotoxicity and low osmolality.

Iohexol mechanism of action

Organic iodine compounds block x-rays as they pass through the body, thereby allowing body structures containing iodine to be delineated in contrast to those structures that do not contain iodine. The degree of opacity produced by these compounds is directly proportional to the total amount (concentration and volume) of the iodinated contrast agent in the path of the x-rays. After intrathecal administration into the subarachnoid space, diffusion of iohexol in the CSF allows the visualization of the subarachnoid spaces of the head and spinal canal. After intravascular administration, iohexol makes opaque those vessels in its path of flow, allowing visualization of the internal structures until significant hemodilution occurs.

Dosage forms of Iohexol

FormRouteStrength
Injectionintrathecal; intravascular; intravenous; oral518 mg/mL
Injectionintravenous140 mg/mL
Injectionintravenous180 mg/mL
Prescription Generics

false

International Brands

Omnipaque

Synonyms

Iohexolum N,N’-Bis(2,3-dihydroxypropyl)-5-(N-(2,3-dihydroxypropyl)acetamido)-2,4,6-triiodoisophthalamide

Manufacturers

GE Healthcare Inc.

CAS number

66108-95-0

UNII

4419T9MX03

State

solid

Affected organisms

Humans and other mammals

Indication of Iohexol

Iohexol ia used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures.

Toxicity of Iohexol

Non-ionic radiocontrast agents like iohexol are cytotoxic to renal cells. The toxic effects include apoptosis, cellular energy failure, disruption of calcium homeostasis, and disturbance of tubular cell polarity, and are thought to be linked to oxidative stress.

RX24 Drugs Disclaimer: before buying a Iohexol on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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