Save up -80% on Iron Dextran
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Infed
|$31.21||1 vial (2ml) 50mg/ml|
|price without discount in nearest pharmacy. Price may vary.|
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Iron Dextran volume of distribution
The initial volume of distribution of iron sucrose (3.4 L) (23), like that of both forms of iron dextran (3.5 L or 55 ml/kg), (24) is equivalent to plasma volume. This is further evidence that early, direct donation of iron to transferrin is limited and relatively inconsequential at low iron doses.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Iron Dextran
Iron dextran is a dark brown, slightly viscous liquid complex of ferric hydroxide and dextran for intravenous or intramuscular use. Iron Dextran is used for the treatment of patients with documented iron deficiency in which oral administration is unsatisfactory or impossible.
Iron Dextran mechanism of action
After iron dextran is injected, the circulating iron dextran is removed from the plasma by cells of the reticuloendothelial system, which split the complex into its components of iron and dextran. The iron is immediately bound to the available protein moieties to form hemosiderin or ferritin, the physiological forms of iron, or to a lesser extent to transferrin. This iron which is subject to physiological control replenishes hemoglobin and depleted iron stores.
Dosage forms of Iron Dextran
|Injection, solution||intravenous||50 mg/mL|
|Injection||intramuscular; intravenous||50 mg/mL|
Dexferrum Dextran iron
Alaven Pharmaceutical LLC
Humans and other mammals
Indication of Iron Dextran
For treatment of patients with documented iron deficiency in whom oral administration is unsatisfactory or impossible. Also used to replenish body iron stores in Non-Dialysis Dependent-Chronic Kidney Disease (NDD-CKD) patients receiving or not receiving erythropoietin and in Hemodialysis Dependent (HDD-CKD) and Peritoneal Dialysis Dependent (PDD-CKD) – Chronic Kidney Disease patients receiving an erythropoietin.
Toxicity of Iron Dextran
LDsub50/sub = 500 mg/kg (mouse, IV). Dosages of iron dextran in excess of the requirements for restoration of hemoglobin and replenishment of iron stores may lead to hemosiderosis. Cases of severe, sometimes fatal, allergic reactions (loss of consciousness, collapse, difficulty breathing, hives, swelling, or convulsions) and severe low blood pressure (hypotension) have been reported with the use of iron dextran.
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