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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Isocarboxazid

Marplan 10 mg tablet



* price without discount in nearest pharmacy. Price may vary.

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Isocarboxazid volume of distribution

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What is Isocarboxazid

An MAO inhibitor that is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in the treatment of panic disorder and the phobic disorders. (From AMA, Drug Evaluations Annual, 1994, p311)

Isocarboxazid mechanism of action

Isocarboxazid works by irreversibly blocking the action of a chemical substance known as monoamine oxidase (MAO) in the nervous system. MAO subtypes A and B are involved in the metabolism of serotonin and catecholamine neurotransmitters such as epinephrine, norepinephrine, and dopamine. Isocarboxazid, as a nonselective MAO inhibitor, binds irreversibly to monoamine oxidasendash;A (MAO-A) and monoamine oxidasendash;B (MAO-B). The reduced MAO activity results in an increased concentration of these neurotransmitters in storage sites throughout the central nervous system (CNS) and sympathetic nervous system. This increased availability of one or more monoamines is the basis for the antidepressant activity of MAO inhibitors.

Dosage forms of Isocarboxazid

Tabletoral10 mg/1
Prescription Generics


International Brands



Isocarboxazida Isocarboxazide


Validus Pharmaceuticals LLC

CAS number






Affected organisms

Humans and other mammals

Indication of Isocarboxazid

May be used to treat major depressive disorder.

Toxicity of Isocarboxazid

Signs of overdose include severe anxiety, confusion, convulsions, cool clammy skin, severe dizziness, severe drowsiness, fast and irregular pulse, fever, hallucinations, severe headache, high or low blood pressure, hyperactive reflexes, muscle stiffness, respiratory depression or failure, slowed reflexes, sweating, severe trouble in sleeping, and unusual irritability.

RX24 Drugs Disclaimer: before buying a Isocarboxazid on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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