Save up -80% on Isoniazid

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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Stanozide

$8.7830 tablets/300mg
Price with discount in nearest pharmacy. Price may vary.

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We offer free Isoniazid coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Isoniazid every time. What are you waiting for? Claim your prescription drug card now!

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Isoniazid volume of distribution

Isoniazid readily diffuses to all body fluids and tissues, with the largest accumulation occurring in the liver. Volume of distribution (Vd): 0.6 l/kg.

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2018 Statistics

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Discount Cards 16,000+


Clients Benefit 29%


Total savings $4,735,080

What is Isoniazid

Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.

Isoniazid mechanism of action

Isoniazid is a prodrug and must be activated by bacterial catalase. Specficially, activation is associated with reduction of the mycobacterial ferric KatG catalase-peroxidase by hydrazine and reaction with oxygen to form an oxyferrous enzyme complex. Once activated, isoniazid inhibits the synthesis of mycoloic acids, an essential component of the bacterial cell wall. At therapeutic levels isoniazid is bacteriocidal against actively growing intracellular and extracellular i Mycobacterium tuberculosis /i organisms. Specifically isoniazid inhibits InhA, the enoyl reductase from i Mycobacterium tuberculosis /i , by forming a covalent adduct with the NAD cofactor. It is the INH-NAD adduct that acts as a slow, tight-binding competitive inhibitor of InhA.

Dosage forms of Isoniazid

Tabletoral300 mg
Injection, solutionintramuscular100 mg/mL
Solutionoral50 mg/5mL

Prescription Generics


International Brands

Dom-isoniazid 300mg Tablets


4-pyridinecarbohydrazide INH


Dominion Pharmacal

CAS number






Affected organisms


Indication of Isoniazid

For the treatment of all forms of tuberculosis in which organisms are susceptible.

Toxicity of Isoniazid

LD sub 50 /sub 100 mg/kg (Human, oral). Adverse reactions include rash, abnormal liver function tests, hepatitis, peripheral neuropathy, mild central nervous system (CNS) effects. In vivo, Isoniazid reacts with pyridoxal to form a hydrazone, and thus inhibits generation of pyridoxal phosphate. Isoniazid also combines with pyridoxal phosphate; high doses interfere with the coenzyme function of the latter.

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Isoniazid on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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