Save up -80% on Isosorbide Dinitrate
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Isordil
|Price with discount in nearest pharmacy. Price may vary.|
We offer free Isordil coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Isosorbide Dinitrate every time. What are you waiting for? Claim your prescription drug card now!
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Isosorbide Dinitrate volume of distribution
The half-life is approximately 5 hours, the volume of distribution is 0.62 liter/kg, and the systemic clearance is 115 mL/min.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Isosorbide Dinitrate
A vasodilator used in the treatment of angina pectoris. Its actions are similar to nitroglycerin but with a slower onset of action.
Isosorbide Dinitrate mechanism of action
Similar to other nitrites and organic nitrates, isosorbide dinitrate is converted to nitric oxide (NO), an active intermediate compound which activates the enzyme guanylate cyclase (atrial natriuretic peptide receptor A). This stimulates the synthesis of cyclic guanosine 3′,5′-monophosphate (cGMP) which then activates a series of protein kinase-dependent phosphorylations in the smooth muscle cells, eventually resulting in the dephosphorylation of the myosin light chain of the smooth muscle fiber. The subsequent release of calcium ions results in the relaxation of the smooth muscle cells and vasodilation.
Dosage forms of Isosorbide Dinitrate
|Isosorbide Dinitrate||5mg||100 Tablet||$23.00|
|Isosorbide Dinitrate||10mg||100 Tablet||$26.00|
|Isosorbide Dinitrate||30mg||100 Tablet||$42.00|
|Isordil CR||40mg||56 Prolonged Release Tablet||$71.00|
1,4:3,6-Dianhydrosorbitol 2,5-dinitrate Carvasin
Arbor Pharmaceuticals, Inc.
Humans and other mammals
Indication of Isosorbide Dinitrate
For the prevention of angina pectoris due to coronary artery disease.
Toxicity of Isosorbide Dinitrate
Symptoms of overdose include reduced cardiac output and hypotension.
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