Save up -80% on Isotretinoin
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Absorica
|$1718.86||60 capsules/40 mg|
|price without discount in nearest pharmacy. Price may vary.|
We offer free Isotretinoin coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Isotretinoin every time. What are you waiting for? Claim your prescription drug card now!
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Isotretinoin volume of distribution
Isotretinoin is extensively bound to plasma proteins (99.9 %) with the result that the free active fraction of the substance is less than 0.1 % of the total over a wide range of therapeutic concentrations. Albumin appears to be the major binding protein. The volume of distribution of isotretinoin is not known in humans since it is not available as an intravenous preparation.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Isotretinoin
Isotretinoin is a medication used for the treatment of severe acne. It is sometimes used in prevention of certain skin cancers. It is a retinoid, meaning it derives from vitamin A and is found in small quantities naturally in the body. Isotretinoin binds to and activates nuclear retinoic acid receptors (RAR), thereby regulating cell proliferation and differentiation. This agent also exhibits immunomodulatory and anti-inflammatory responses and inhibits ornithine decarboxylase, thereby decreasing polyamine synthesis and keratinization.
Isotretinoin mechanism of action
Isotretinoin noticeably reduces the production of sebum and shrinks the sebaceous glands. It stabilises keratinization and prevents comedones from forming. It also reduces inflammation in moderate-severe inflammatory acne. The exact mechanism of action is unknown, however it is known that it alters DNA transcription.
Dosage forms of Isotretinoin
(7e,9e,11e,13Z)-Retinoic acid 13-cis-Retinoic acid
Ranbaxy Laboratories Inc.
Humans and other mammals
Indication of Isotretinoin
For the treatment of severe recalcitrant nodular acne
Toxicity of Isotretinoin
Isotretinoin is teratogenic. It also causes mucocutaneous side effects suck as cheilitis, dry skin, and dry eyes.
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