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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Ivermectin

Stromectol 3 mg tablet



* price without discount in nearest pharmacy. Price may vary.

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Ivermectin volume of distribution

The volume of distribution is 3 to 3.5 L/kg and it does not cross the blood-brain barrier.

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What is Ivermectin

Ivermectin is a broad-spectrum anti-parasite medication. It was first marketed under the name Stromectol and used against worms (except tapeworms), but, in 2012, it was approved for the topical treatment of head lice infestations in patients 6 months of age and older, and marketed under the name Sklice as well. Ivermectin is mainly used in humans in the treatment of onchocerciasis, but is also effective against other worm infestations (such as strongyloidiasis, ascariasis, trichuriasis and enterobiasis).

Ivermectin mechanism of action

Ivermectin binds selectively and with high affinity to glutamate-gated chloride ion channels in invertebrate muscle and nerve cells of the microfilaria. This binding causes an increase in the permeability of the cell membrane to chloride ions and results in hyperpolarization of the cell, leading to paralysis and death of the parasite. Ivermectin also is believed to act as an agonist of the neurotransmitter gamma-aminobutyric acid (GABA), thereby disrupting GABA-mediated central nervous system (CNS) neurosynaptic transmission. Ivermectin may also impair normal intrauterine development of O. volvulus microfilariae and may inhibit their release from the uteri of gravid female worms.

Dosage forms of Ivermectin

Creamtopical1 %
Lotiontopical.585 g/117g
Lotiontopical5 mg/g
Prescription Generics


International Brands



Ivermectin Ivermectina


Edenbridge Pharmaceuticals, LLC

CAS number






Affected organisms

Parasitic nematodes and other roundworms

Indication of Ivermectin

For the treatment of intestinal (i.e., nondisseminated) strongyloidiasis due to the nematode parasite iStrongyloides stercoralis /i. Also for the treatment of onchocerciasis (river blindness) due to the nematode parasite iOnchocerca volvulus /i. Can be used to treat scabies caused by iSarcoptes scabiei /i.

Toxicity of Ivermectin

LD sub50 /sub = 29.5 mg/kg (Mouse, oral). LD sub50 /sub = 10 mg/kg (Rat, oral). Adverse effects include muscle or joint pain, dizziness, fever, headache, skin rash, fast heartbeat.

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