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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Sklice

$348.581 tube (117g) 0.5% lotion
price without discount in nearest pharmacy. Price may vary.

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Ivermectin volume of distribution

Due to the high lipid solubility of ivermectin, this compound is widely distributed within the body. In healthy men, the volume of distribution in the central compartment, Vc, was 3.1 and 3.5 l. kg−1, after ingesting 6 and 12 mg of ivermectin, respectively.

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What is Ivermectin

Ivermectin is a broad-spectrum anti-parasite medication. It was first marketed under the name Stromectol and used against worms (except tapeworms), but, in 2012, it was approved for the topical treatment of head lice infestations in patients 6 months of age and older, and marketed under the name Sklice as well. Ivermectin is mainly used in humans in the treatment of onchocerciasis, but is also effective against other worm infestations (such as strongyloidiasis, ascariasis, trichuriasis and enterobiasis).

Ivermectin mechanism of action

Ivermectin binds selectively and with high affinity to glutamate-gated chloride ion channels in invertebrate muscle and nerve cells of the microfilaria. This binding causes an increase in the permeability of the cell membrane to chloride ions and results in hyperpolarization of the cell, leading to paralysis and death of the parasite. Ivermectin also is believed to act as an agonist of the neurotransmitter gamma-aminobutyric acid (GABA), thereby disrupting GABA-mediated central nervous system (CNS) neurosynaptic transmission. Ivermectin may also impair normal intrauterine development of O. volvulus microfilariae and may inhibit their release from the uteri of gravid female worms.

Dosage forms of Ivermectin

DrugDosageQuantityPrice
Soolantra Cream1%30g Cream$150.00
Soolantra Cream1%90g Cream$418.00
Ivermectin3mg20 Tablet$132.00
Ivermectin6mg50 Dispersible Tablet$123.00
Ivermectin12mg50 Tablet$140.00
Heartgard Plus Chewables Brown (for dogs over 50lbs)272mcg/227mg6 Chewable Tablets$47.00

Prescription Generics

true

International Brands

Ivermectin

Synonyms

Ivermectin Ivermectina

Manufacturers

Edenbridge Pharmaceuticals, LLC

CAS number

70288-86-7

UNII

8883YP2R6D

State

solid

Affected organisms

Parasitic nematodes and other roundworms

Indication of Ivermectin

For the treatment of intestinal (i.e., nondisseminated) strongyloidiasis due to the nematode parasite Strongyloides stercoralis. Also for the treatment of onchocerciasis (river blindness) due to the nematode parasite Onchocerca volvulus. Can be used to treat scabies caused by Sarcoptes scabiei.

Toxicity of Ivermectin

LD sub50 /sub = 29.5 mg/kg (Mouse, oral). LD sub50 /sub = 10 mg/kg (Rat, oral). Adverse effects include muscle or joint pain, dizziness, fever, headache, skin rash, fast heartbeat.

RX24 Drugs Disclaimer: before buying a Ivermectin on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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What is Sklice lotion?

The US Food and Drug Administration (FDA) approved Sklice lotion, 0.5% for topical treatment of head lice, in patients 6 months and older. Effective and well tolerated, Sklice Lotion treats lice in most patients with a single 10-minute lotion.

Sklice Lotion contains a broad-spectrum anti-parasitic agent, ivermectin, which was developed from a soil bacterium that produces a family of compounds (avermectins) that have been shown to bind selectively and with high affinity to certain ion channels present in invertebrate nerve and muscle cells. but not in mammals. The resulting increased permeability of the cell membrane causes paralysis and death in some parasites.

The widespread oral use of ivermectin began in 1987 to control river blindness (onchocerciasis) in humans. More than one billion treatments of ivermectin tablets have been carried out to help alleviate the suffering caused by river blindness and other parasitic conditions.

For use only on the hair of the head. Do not use ivermectin lotion in the eyes, mouth, or vagina. Read the patient information that comes with Sklice lotion. This leaflet does not replace a conversation with your doctor about your medical condition or treatment.

What is Soolantra?

The US Food and Drug Administration (FDA) approved Soolantra cream (ivermectin), 1% for a single daily treatment of inflammatory lesions or bumps and rosacea pimples. Recent studies have shown that usually harmless demodex microscopic mites can cause rosacea. Sulantra has both anti-inflammatory and antiparasitic activity. Soolantra is used to treat rosacea.