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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Taltz

$5,134

80mg/ml

* price without discount in nearest pharmacy. Price may vary.

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Ixekizumab volume of distribution

The mean (geometric CV%) volume of distribution at steady-state was 7.11 L (29%) in subjects with plaque psoriasis.

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What is Ixekizumab

Ixekizumab is a humanized immunoglobulin G subclass 4 (IgG4) monoclonal antibody (mAb) against interleukin-17A (IL-17A) and prevents it from interacting with the IL-17A receptor. As IL-17A is a pro-inflammatory cytokine involved in inflammation and immune responses, blocking its effect is beneficial for use in inflammatory conditions. In particular, IL-17A has been found to be implicated in a variety of autoimmune diseases including Rheumatoid Arthritis and plaque psoriasis. Ixekizumab is produced by recombinant DNA technology in a recombinant mammalian cell line and purified using standard technology for bioprocessing. Ixekizumab is comprised of two identical light chain polypeptides of 219 amino acids each and two identical heavy chain polypeptides of 445 amino acids each, and has a molecular weight of 146,158 Daltons for the protein backbone of the molecule. It is indicated for the treatment of adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy.

Ixekizumab mechanism of action

Ixekizumab is a humanized immunoglobulin G subclass 4 (IgG4) monoclonal antibody (mAb) against interleukin-17A (IL-17A) and prevents it from interacting with the IL-17A receptor. As IL-17A is a pro-inflammatory cytokine involved in inflammation and immune responses, blocking its effect is beneficial for use in inflammatory conditions. In particular, IL-17A has been found to be implicated in a variety of autoimmune diseases including Rheumatoid Arthritis and plaque psoriasis.

Dosage forms of Ixekizumab

DrugDosageQuantityPrice
Taltz80mg/ml1 carton (1 autoinjector)$5,143
Taltz80mg/ml1 carton (1 syringe)$5,143
Taltz80mg/ml1 carton (2 autoinjectors)$10,259
Taltz80mg/ml1 carton (2 syringes)$10,259
Taltz80mg/ml1 carton (3 autoinjectors)$15,385
Taltz80mg/ml1 carton (3 syringes)$15,804
Prescription Generics

false

International Brands

Taltz

Synonyms

Manufacturers

Eli Lilly and Company

CAS number

1143503-69-8

UNII

BTY153760O

State

solid

Affected organisms

Indication of Ixekizumab

Ixekizumab is indicated for the treatment of adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy.

Toxicity of Ixekizumab

The most common adverse reactions associated with Ixekizumab treatment are injection site reactions, upper respiratory tract infections, nausea, and tinea infections.

RX24 Drugs Disclaimer: before buying a Ixekizumab on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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