Save up -80% on Ketoconazole

Note: this is a drug discount program, not an insurance plan.

RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Ketoconazole

Ketoconazole 2% cream



* price without discount in nearest pharmacy. Price may vary.

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Ketoconazole volume of distribution

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What is Ketoconazole

Broad spectrum antifungal agent used for long periods at high doses, especially in immunosuppressed patients.

Ketoconazole mechanism of action

Ketoconazole interacts with 14-alpha; demethylase, a cytochrome P-450 enzyme necessary for the conversion of lanosterol to ergosterol. This results in inhibition of ergosterol synthesis and increased fungal cellular permeability. Other mechanisms may involve the inhibition of endogenous respiration, interaction with membrane phospholipids, inhibition of yeast transformation to mycelial forms, inhibition of purine uptake, and impairment of triglyceride and/or phospholipid biosynthesis. Ketoconazole can also inhibit the synthesis of thromboxane and sterols such as aldosterone, cortisol, and testosterone.

Dosage forms of Ketoconazole

Aerosol, foamtopical20 mg/g
Aerosol, foamtopical2 g/100g
Creamtopical20 mg/g
Prescription Generics


International Brands



Extina Ketoconazol


Apotex Inc

CAS number






Affected organisms


Indication of Ketoconazole

For the treatment of the following systemic fungal infections: candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis.

Toxicity of Ketoconazole

Hepatotoxicity, LD sub 50 /sub =86 mg/kg (orally in rat)

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