Save up -80% on Ketoprofen
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Orudis
|$20||30 capsules/75 mg|
|Price with discount in nearest pharmacy. Price may vary.|
We offer free Ketoprofen coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Ketoprofen every time. What are you waiting for? Claim your prescription drug card now!
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Ketoprofen volume of distribution
The apparent volume of distribution (Vd/F) was approximately 10-15% of body weight. The renal contribution (mean, 0.10-0.15 ml/min/kg) to the plasma clearance of free ketoprofen was assumed to be, at most, 8.3-12.9%.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Ketoprofen
Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with analgesic and antipyretic properties.
Ketoprofen mechanism of action
The anti-inflammatory effects of ketoprofen are believed to be due to inhibition cylooxygenase-2 (COX-2), an enzyme involved in prostaglandin synthesis via the arachidonic acid pathway. This results in decreased levels of prostaglandins that mediate pain, fever and inflammation. Ketoprofen is a non-specific cyclooxygenase inhibitor and inhibition of COX-1 is thought to confer some of its side effects, such as GI upset and ulceration. Ketoprofen is thought to have anti-bradykinin activity, as well as lysosomal membrane-stabilizing action. Antipyretic effects may be due to action on the hypothalamus, resulting in an increased peripheral blood flow, vasodilation, and subsequent heat dissipation.
Dosage forms of Ketoprofen
2-(3-Benzoylphenyl)propionic acid 3-Benzoyl-alpha-methylbenzeneacetic acid
Physicians Total Care, Inc.
Humans and other mammals
Indication of Ketoprofen
For symptomatic treatment of acute and chronic rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, primary dysmenorrhea and mild to moderate pain associated with musculotendinous trauma (sprains and strains), postoperative (including dental surgery) or postpartum pain.
Toxicity of Ketoprofen
LD sub 50 /sub =62.4 mg/kg (rat, oral). p Symptoms of overdose include drowsiness, vomiting and abdominal pain. /p p Side effects are usually mild and mainly involved the GI tract. Most common adverse GI effect is dyspepsia (11% of patients). May cause nausea, diarrhea, abdominal pain, constipation and flatulence in greater than 3% of patients.
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