Save up -80% on Ketorolac
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Toradol
|$17.06||20 tablets/10 mg|
|price without discount in nearest pharmacy. Price may vary.|
We offer free Ketorolac coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Ketorolac every time. What are you waiting for? Claim your prescription drug card now!
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Ketorolac volume of distribution
* 0.26 0.08 L/kg (children 4 to 8 years old)
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Ketorolac
Ketorolac mechanism of action
Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) chemically related to indomethacin and tolmetin. Ketorolac tromethamine is a racemic mixture of (-)S- and (+)R-enantiomeric forms, with the S-form having analgesic activity. Its antiinflammatory effects are believed to be due to inhibition of both cylooxygenase-1 (COX-1) and cylooxygenase-2 (COX-2) which leads to the inhibition of prostaglandin synthesis leading to decreased formation of precursors of prostaglandins and thromboxanes from arachidonic acid. The resultant reduction in prostaglandin synthesis and activity may be at least partially responsible for many of the adverse, as well as the therapeutic, effects of these medications. Analgesia is probably produced via a peripheral action in which blockade of pain impulse generation results from decreased prostaglandin activity. However, inhibition of the synthesis or actions of other substances that sensitize pain receptors to mechanical or chemical stimulation may also contribute to the analgesic effect. In terms of the ophthalmic applications of ketorolac – ocular administration of ketorolac reduces prostaglandin E2 levels in aqueous humor, secondary to inhibition of prostaglandin biosynthesis.
Dosage forms of Ketorolac
|Solution/ drops||ophthalmic||5 mg/mL|
(+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid (+-)-Ketorolac
Humans and other mammals
Indication of Ketorolac
For the short-term (~5 days) management of moderately severe acute pain that requires analgesia at the opioid level, usually in a postoperative setting.
Toxicity of Ketorolac
LD sub50 /sub = 189 mg/kg (rat, oral).
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