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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Aminosyn II

Price with discount in nearest pharmacy. Price may vary.

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L-Aspartic Acid volume of distribution

The effects of poly-L-aspartic acid on the pharmacokinetics of gentamicin were examined by using a randomized crossover trial design with the dog. When analyzed according to a three-compartment open model, poly-L-aspartic acid reduced some first-order rate equation constants (A3, lambda 1, and lambda 3), the deep peripheral compartment exit microconstant (k31), the elimination rate constant (k(el)), and the area under the concentration-time curve from 0 to 480 h (AUC0-480) (0.21-, 0.60-, 0.26-, 0.27-, 0.72-, and 0.76-fold, respectively; P < 0.05) but increased the volume of distribution at steady state (Vss), the volume of distribution calculated by the area method (V(area)), the apparent volume of the peripheral compartment (Vp), and all mean time parameters.

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What is L-Aspartic Acid

One of the non-essential amino acids commonly occurring in the L-form. It is found in animals and plants, especially in sugar cane and sugar beets. It may be a neurotransmitter.

L-Aspartic Acid mechanism of action

There are also claims that L-aspartate has ergogenic effects, that it enhances performance in both prolonged exercise and short intensive exercise. It is hypothesized that L-aspartate, especially the potassium magnesium aspartate salt, spares stores of muscle glycogen and/or promotes a faster rate of glycogen resynthesis during exercise. It has also been hypothesized that L-aspartate can enhance short intensive exercise by serving as a substrate for energy production in the Krebs cycle and for stimulating the purine nucleotide cycle.

Dosage forms of L-Aspartic Acid

Injection, solutionintravenous
Injection, solution, concentrateintravenous

Prescription Generics


International Brands

Aminosyn II


(S)-2-aminobutanedioic acid (S)-2-aminosuccinic acid


Hospira, Inc.

CAS number






Affected organisms

Humans and other mammals

Indication of L-Aspartic Acid

There is no support for the claim that aspartates are exercise performance enhancers, i.e. ergogenic aids.

Toxicity of L-Aspartic Acid

Mild gastrointestinal side effects including diarrhea. LD sub 50 /sub (rat) 5,000 mg/kg.

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