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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of L-Tryptophan

Tryptan 750 mg Tablet

$1.2

tablet

* price without discount in nearest pharmacy. Price may vary.

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What is L-Tryptophan

An essential amino acid that is necessary for normal growth in infants and for nitrogen balance in adults. It is a precursor of indole alkaloids in plants. It is a precursor of serotonin (hence its use as an antidepressant and sleep aid). It can be a precursor to niacin, albeit inefficiently, in mammals.

L-Tryptophan mechanism of action

A number of important side reactions occur during the catabolism of tryptophan on the pathway to acetoacetate. The first enzyme of the catabolic pathway is an iron porphyrin oxygenase that opens the indole ring. The latter enzyme is highly inducible, its concentration rising almost 10-fold on a diet high in tryptophan. Kynurenine is the first key branch point intermediate in the pathway. Kynurenine undergoes deamniation in a standard transamination reaction yielding kynurenic acid. Kynurenic acid and metabolites have been shown to act as antiexcitotoxics and anticonvulsives. A second side branch reaction produces anthranilic acid plus alanine. Another equivalent of alanine is produced further along the main catabolic pathway, and it is the production of these alanine residues that allows tryptophan to be classified among the glucogenic and ketogenic amino acids. The second important branch point converts kynurenine into 2-amino-3-carboxymuconic semialdehyde, which has two fates. The main flow of carbon elements from this intermediate is to glutarate. An important side reaction in liver is a transamination and several rearrangements to produce limited amounts of nicotinic acid, which leads to production of a small amount of NAD sup + /sup and NADP sup + /sup .

Dosage forms of L-Tryptophan

DrugDosageQuantityPrice
Tryptophan500mg100 Tablet$77.00
Tryptophan1g100 Tablet$119.00
Tryptan250mg100 Tablet$79.00
Tryptan500mg100 Tablet$135.50
Tryptan750mg100 Tablet$192.50
Tryptan1000mg100 Tablet$249.00
Prescription Generics

false

International Brands

2.5% Travasol Amino Acid Injection With Electrolytes In 10% Dextrose

Synonyms

(-)-Tryptophan (2S)-2-amino-3-(1H-indol-3-yl)Propanoic acid

Manufacturers

Baxter Corporation Clintec Nutrition Division

CAS number

73-22-3

UNII

8DUH1N11BX

State

solid

Affected organisms

Humans and other mammals

Indication of L-Tryptophan

Tryptophan may be useful in increasing serotonin production, promoting healthy sleep, managing depression by enhancing mental and emotional well-being, managing pain tolerance, and managing weight.

Toxicity of L-Tryptophan

Oral rat LD sub 50 /sub : 16 gm/kg. Investigated as a tumorigen, mutagen, reproductive effector. Symptoms of overdose include agitation, confusion, diarrhea, fever, overactive reflexes, poor coordination, restlessness, shivering, sweating, talking or acting with excitement you cannot control, trembling or shaking, twitching, and vomiting.

RX24 Drugs Disclaimer: before buying a L-Tryptophan on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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