Save up -80% on Lamivudine

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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Lamivudine

Epivir 150 mg tablet



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Lamivudine volume of distribution

Apparent volume of distribution, IV administration = 1.3 0.4 L/kg. Volume of distribution was independent of dose and did not correlate with body weight.

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What is Lamivudine

A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3#39; carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).

Lamivudine mechanism of action

Lamivudine is a synthetic nucleoside analogue and is phosphorylated intracellularly to its active 5′-triphosphate metabolite, lamivudine triphosphate (L-TP). This nucleoside analogue is incorporated into viral DNA by HIV reverse transcriptase and HBV polymerase, resulting in DNA chain termination.

Dosage forms of Lamivudine

Form Route Strength
Solution oral 10 mg
Tablet oral 150 mg
Tablet oral 300 mg
Prescription Generics


International Brands



(-)-1-((2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine (-)-2′-Deoxy-3′-thiacytidine


Viiv Healthcare Ulc

CAS number






Affected organisms

Human Immunodeficiency Virus

Indication of Lamivudine

For the treatment of HIV infection and chronic hepatitis B (HBV).

Toxicity of Lamivudine

The most common reported adverse reactions (incidence 15%) in adults were headache, nausea, malaise and fatigue, nasal signs and symptoms, diarrhea, and cough.

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