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2018 Price of Laronidase
Aldurazyme 2.9 mg/5 ml vial
ml
* price without discount in nearest pharmacy. Price may vary.
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Laronidase volume of distribution
About RX24Drugs
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What is Laronidase
Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology in a Chinese hamster ovary cell line. Laronidase is a glycoprotein with a molecular weight of approximately 83 kD. The predicted amino acid sequence of the recombinant form, as well as the nucleotide sequence that encodes it, are identical to a polymorphic form of human a-L-iduronidase. It contains 6 N-linked oligosaccharide modification sites.
Laronidase mechanism of action
Laronidase catalyses the hydrolysis of terminal alpha-L-iduronic acid residues of dermatan sulfate and heparin sulfate.
Dosage forms of Laronidase
| Form | Route | Strength |
|---|---|---|
| Concentrate for solution for infusion | Intravenous use | 100 U/ml |
| Injection, solution, concentrate | intravenous | 2.9 mg/5mL |
| Solution | intravenous | 0.58 mg |
Prescription Generics
false
International Brands
Aldurazyme
Synonyms
Alpha-L-iduronidase precursor
Manufacturers
Genzyme Corporation
CAS number
210589-09-6
UNII
WP58SVM6R4
State
liquid
Affected organisms
Humans and other mammals
Indication of Laronidase
For the treatment of mucopolysaccharidosis
Toxicity of Laronidase
RX24 Drugs Disclaimer: before buying a Laronidase on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.
