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Price of Laronidase
Aldurazyme 2.9 mg/5 ml vial
* price without discount in nearest pharmacy. Price may vary.
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Laronidase volume of distribution
What is Laronidase
Human recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology in a Chinese hamster ovary cell line. Laronidase is a glycoprotein with a molecular weight of approximately 83 kD. The predicted amino acid sequence of the recombinant form, as well as the nucleotide sequence that encodes it, are identical to a polymorphic form of human a-L-iduronidase. It contains 6 N-linked oligosaccharide modification sites.
Laronidase mechanism of action
Laronidase catalyses the hydrolysis of terminal alpha-L-iduronic acid residues of dermatan sulfate and heparin sulfate.
Dosage forms of Laronidase
|Concentrate for solution for infusion||Intravenous use||100 U/ml|
|Injection, solution, concentrate||intravenous||2.9 mg/5mL|
Humans and other mammals
Indication of Laronidase
For the treatment of mucopolysaccharidosis
Toxicity of Laronidase
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