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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

Pharmacists and Patients support.

2018 Price of Zurampic

$192

15 tablets (200mg)

* price without discount in nearest pharmacy. Price may vary.

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Lesinurad volume of distribution

The mean steady state volume of distribution of lesinurad was approximately 20 L following intravenous dosing.

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What is Lesinurad

Lesinurad is an oral uric acid transporter 1 (URAT1) inhibitor indicated for the treatment of hyperuricemia associated with gout. It reduces serum uric acid concentration through the inhibition of URAT1, an enzyme responsible for reuptake of uric acid from the renal tubule, and OAT4, another uric acid transporter associated with diuretic-induced hyperuricemia. Marketed as the product Zurampic, it is indicated for use in combination with a xanthine oxidase inhibitor for the treatment of hyperuricemia associated with gout in patients who have not achieved target serum uric acid levels with a xanthine oxidase inhibitor alone.

Lesinurad mechanism of action

Lesinurad inhibits the activity of uric acid transporter 1 (URAT1) and organic anion transporter 4 (OAT4). URAT1 is a major transporter enzyme responsible for reuptake of uric acid from the renal tubules; inhibition of URAT1 function thereby increases excretion of uric acid.

Dosage forms of Lesinurad

DrugDosageQuantityPrice
Zurampic200mg15 tablets$196
Zurampic200mg30 tablets$376
Zurampic200mg90 tablets$1,106
Prescription Generics

false

International Brands

Zurampic

Synonyms

{[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid

Manufacturers

Astra Zeneca Pharmaceuticals Lp

CAS number

878672-00-5

UNII

09ERP08I3W

State

solid

Affected organisms

Indication of Lesinurad

For use, in combination with a xanthine oxidase inhibitor, for the treatment of hyperuricemia associated with gout in patients who have not achieved target serum uric acid levels with a xanthine oxidase inhibitor alone.

Toxicity of Lesinurad

RX24 Drugs Disclaimer: before buying a Lesinurad on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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