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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

Pharmacists and Patients support.

2018 Price of Xyzal

$144

5mg (100 tablets)

* price without discount in nearest pharmacy. Price may vary.

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Levocetirizine volume of distribution

Approximately 0.4 L/kg.

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What is Levocetirizine

Levocetirizine is a third-generation non-sedative antihistamine indicated for the relief of symptoms associated with seasonal and perennial allergic rhinitis and uncomplicated skin manifestations of chronic idiopathic urticaria. It was developed from the second-generation antihistamine cetirizine. Levocetirizine is the R-enantiomer of the cetirizine racemate. Levocetirizine is an inverse agonist that decreases activity at histamine H1 receptors. This in turn prevents the release of other allergy chemicals and increased blood supply to the area, and provides relief from the typical symptoms of hay fever. It does not prevent the actual release of histamine from mast cells. Levocetirizine was approved by the United States Food and Drug Administration on May 25, 2007 and is marketed under the brand XYZAL by sanofi-aventis U.S. LLC.

Levocetirizine mechanism of action

Levocetirizine, the active enantiomer of cetirizine, is an anti-histamine; its principal effects are mediated via selective inhibition of H1 receptors. The antihistaminic activity of levocetirizine has been documented in a variety of animal and human models. In vitro binding studies revealed that levocetirizine has an affinity for the human H1-receptor 2-fold higher than that of cetirizine (Ki = 3 nmol/L vs. 6 nmol/L, respectively). This increased affinity has unknown clinical relevance.

Dosage forms of Levocetirizine

DrugDosageQuantityPrice
Xyzal5mg100 Tablet$144.00
Xyzal Oral Solution0.5mg/mL200mL Solution$75.00
Levocetirizine5mg100 Tablet$60.00
Prescription Generics

true

International Brands

Levocetirizine Dihydrochloride

Synonyms

2-(2-{4-[(R)-(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid

Manufacturers

Camber Pharmaceuticals, Inc.

CAS number

130018-77-8

UNII

6U5EA9RT2O

State

solid

Affected organisms

Humans and other mammals

Indication of Levocetirizine

Levocetirizine is indicated for the relief of symptoms associated with allergic rhinitis (seasonal and perennial) in adults and children 6 years of age and older.

Toxicity of Levocetirizine

RX24 Drugs Disclaimer: before buying a Levocetirizine on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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