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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Lidocaine

Lidamantle 3% cream



* price without discount in nearest pharmacy. Price may vary.

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Lidocaine volume of distribution

* 0.7 to 2.7 L/kg (healthy volunteers)

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What is Lidocaine

A local anesthetic and cardiac depressant used as an antiarrhythmia agent. Its actions are more intense and its effects more prolonged than those of procaine but its duration of action is shorter than that of bupivacaine or prilocaine.

Lidocaine mechanism of action

Lidocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses thereby effecting local anesthetic action. Lidocaine alters signal conduction in neurons by blocking the fast voltage gated sodium (Na+) channels in the neuronal cell membrane that are responsible for signal propagation. With sufficient blockage the membrane of the postsynaptic neuron will not depolarize and will thus fail to transmit an action potential. This creates the anaesthetic effect by not merely preventing pain signals from propagating to the brain but by aborting their birth in the first place.

Dosage forms of Lidocaine

Form Route Strength
Solution intravenous 20 mg
Liquid subarachnoidal
Prescription Generics


International Brands

0.4% Lidocaine Hydrochloride and 5% Dextrose Injection USP


2-(Diethylamino)-2′,6′-acetoxylidide 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide


Hospira Healthcare Corporation

CAS number






Affected organisms

Humans and other mammals

Indication of Lidocaine

For production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks.

Toxicity of Lidocaine

The oral LD 50 of lidocaine HCl in non-fasted female rats is 459 (346-773) mg/kg (as the salt) and 214 (159-324) mg/kg (as the salt) in fasted female rats. Symptoms of overdose include convulsions, hypoxia, acidosis, bradycardia, arrhythmias and cardiac arrest.

RX24 Drugs Disclaimer: before buying a Lidocaine on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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