Save up -80% on Linagliptin

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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Linagliptin


* price without discount in nearest pharmacy. Price may vary.

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Linagliptin volume of distribution

Vd = 1110 L

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What is Linagliptin

Linagliptin is a DPP-4 inhibitor developed by Boehringer Ingelheim for the treatment of type II diabetes[Wikipedia]. Two pharmacological characteristics that sets linagliptin apart from other DPP-4 inhibitors is that it has a non-linear pharmacokinetic profile and is not primarily eliminated by the renal system. FDA approved on May 2, 2011.

Linagliptin mechanism of action

Linagliptin is a competitive and reversible dipeptidyl peptidase (DPP)-4 enzyme inhibitor that slows the breakdown of insulinotropic hormone glucagon-like peptide (GLP)-1 for better glycemic control in diabetes patients. GLP and glucose-dependent insulinotropic polypeptide (GIP) are incretin hormones that increase the production and release of insulin from pancreatic beta cells and decrease the release of glucagon from pancreatic alpha cells. This results in a overall decrease in glucose production in the liver and increase an of insulin in a glucose-dependent manner.

Dosage forms of Linagliptin

Tablet, film coatedoral
Tablet, film coated, extended releaseoral
Prescription Generics


International Brands



(R)-8-(3-Aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methylquinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione BI 1356


Boehringer Ingelheim Pharmaceuticals, Inc.

CAS number






Affected organisms

Humans and other mammals

Indication of Linagliptin

Linagliptin is used for the management of type 2 diabetes mellitus.

Toxicity of Linagliptin

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