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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Lisdexamfetamine

Vyvanse 60 mg capsule

$5.02

capsule

* price without discount in nearest pharmacy. Price may vary.

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Lisdexamfetamine volume of distribution

NameDosageStrengthRouteLabeller
VyvanseCapsule10 mg/1OralAvera Mc Kennan Hospital
VyvanseCapsule20 mg/1OralShire
VyvanseCapsule30 mg/1OralPhysicians Total Care
VyvanseCapsule40 mg/1OralShire Pharma Canada
VyvanseCapsule50 mg/1OralPhysicians Total Care
VyvanseTablet, chewable60 mg/1OralShire
VyvanseCapsule70 mg/1OralPhysicians Total Care

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What is Lisdexamfetamine

Lisdexamfetamine (L-lysine-d-amphetamine) is a prodrug of the psychostimulant d-amphetamine coupled with the essential amino acid L-lysine. It was developed so that the amphetamine psychostimulant is released and activated more slowly as the prodrug molecule is hydrolyzed consequently cleaving off the amino acid-during the first pass through the intestines and/or the liver. Amphetamines target the trace amine-associated receptor 1 (TAAR1). Amphetamine is also believed to exert its effects by binding to the monoamine transporters (the dopamine transporter or DAT) and increasing extracellular levels of the biogenic amines dopamine, norepinephrine (noradrenaline) and serotonin.

Lisdexamfetamine mechanism of action

Lisdexamfetamine is a pro-drug of dextroamphetamine. Amphetamines are thought to block the reuptake of norepinephrine and dopamine into the presynaptic neuron and increase the release of these monoamines into the extraneuronal space. Norepinephrine and dopamine contribute to maintaining alertness, increasing focus, and sustaining thought, effort, and motivation. However, the exact therapeutic action in ADHD is not known.

Dosage forms of Lisdexamfetamine

DrugDosageQuantityPrice
Loestrin 28 Day1/20mcg3 Packs$69.00
Loestrin 28 Day1.5/30mcg3 Packs$69.00
Loestrin 21 Day1/20mcg6 Packs$87.00
Loestrin 21 Day1.5/30mcg6 Packs$87.00
Lozol2.5mg100 Tablet$89.00
Zoloft25mg100 Capsule$131.20
Zoloft50mg84 Tablet$100.00
Lysteda650mg90$580.00
Lysodren500mg100 Tablet$520.00
Hydroquinone0,0490g Cream$50.00
Prescription Generics

non-available

International Brands

Vyvanse

Synonyms

Lisdexamfetamine, Lisdexamfetamine dimesylate

Manufacturers

Avera Mc Kennan Hospital, Lake Erie Medical&Surgical , Supply Dba Quality Care Products Llc, Physicians Total Care, Shire, Shire Pharma Canada

CAS number

608137-32-2

UNII

H645GUL8KJ

State

solid

Affected organisms

Humans and other mammals

Indication of Lisdexamfetamine

For the treatment of Attention Deficit/Hyperactivity Disorder (ADHD) in pediatric populations aged 6 to 12 years.

Toxicity of Lisdexamfetamine

Manifestations of acute overdosage with amphetamines include restlessness, tremor, hyperreflexia, rapid respiration, confusion, assaultiveness, hallucinations, panic states, hyperpyrexia and rhabdomyolysis. Fatigue and depression usually follow the central nervous system stimulation. Cardiovascular effects include arrhythmias, hypertension or hypotension and circulatory collapse. Gastrointestinal symptoms include nausea, vomiting, diarrhea, and abdominal cramps. Fatal poisoning is usually preceded by convulsions and coma.

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