Save up -80% on Lomitapide

Note: this is a drug discount program, not an insurance plan.

RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Lomitapide


* price without discount in nearest pharmacy. Price may vary.

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Lomitapide volume of distribution

The steady state volume of distribution is about 985-1292 L.

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What is Lomitapide

Lomitapide is a microsomal triglyceride transfer protein (MTP) inhibitor used in homozygous familial hypercholesterolemia (HoFH) patients. It is marketed under the name Juxtapid (R).

Lomitapide mechanism of action

Within the lumen of the endoplasmic reticulum, lomitapide inhibits microsomal triglyceride transfer protein (MTP), which prevents the formation of apolipoprotein B, and, thus, the formation of VLDL and chylomicrons as well. Altogether, this leads to a reduction of low-density lipoprotein cholesterol.

Dosage forms of Lomitapide

Capsuleoral10 mg
Capsuleoral10 mg/1
Capsuleoral20 mg
Prescription Generics


International Brands



AEGR 733 BMS 201038


Aegerion Pharmaceuticals Canada Ltd

CAS number






Affected organisms

Humans and other mammals

Indication of Lomitapide

Used in homozygous familial hypercholesterolemia (HoFH) patients to reduce low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), apolipoprotein B (apo B), and non-high-density lipoprotein cholesterol (non-HDL-C).

Toxicity of Lomitapide

Contra-indicated in pregnancy, and moderate to severe hepatic insufficiency (Child-Pugh category B or C). Severe GI adverse reactions may occur.

RX24 Drugs Disclaimer: before buying a Lomitapide on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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