Save up -80% on Loperamide

Note: this is a drug discount program, not an insurance plan.
RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Imodium

$12.0130 capsules/2 mg
Price with discount in nearest pharmacy. Price may vary.

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We offer free Loperamide coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Loperamide every time. What are you waiting for? Claim your prescription drug card now!

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Loperamide volume of distribution

Based on literature information, the plasma protein binding of loperamide is about 95%. Loperamide is a P-glycoprotein substrate. Elimination The apparent elimination half-life of loperamide is 10.8 hours with a range of 9.1 to 14.4 hours

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2018 Statistics

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Discount Cards 16,000+


Clients Benefit 29%


Total savings $4,735,080

What is Loperamide

One of the long-acting synthetic antidiarrheals; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.

Loperamide mechanism of action

iIn vitro/i and animal studies show that Loperamide acts by slowing intestinal motility and by affecting water and electrolyte movement through the bowel. Loperamide inhibits peristaltic activity by a direct effect on the circular and longitudinal muscles of the intestinal wall. It is a non-selective calcium channel blocker and binds to opioid mu-receptors. Evidence also suggests that at higher concentrations it binds to calmodulin.

Dosage forms of Loperamide

Capsule, liquid filledoral2 mg/1
Tabletoral2 mg/1
Solutionoral.2 mg

Prescription Generics


International Brands

7 Select Anti Diarrheal


Loperamid Loperamida


7 Eleven

CAS number






Affected organisms

Humans and other mammals

Indication of Loperamide

For the control and symptomatic relief of acute nonspecific diarrhea and of chronic diarrhea associated with inflammatory bowel disease or gastroenteritis. Also used for reducing the volume of discharge from ileostomies.

Toxicity of Loperamide

Oral, mouse: LDsub50/sub = 105 mg/kg. Symptoms of overdose include constipation, drowsiness, lethargy, and nausea.

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