Save up -80% on Loperamide

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Loperamide

Loperamide hcl powder

$26.01

g

* price without discount in nearest pharmacy. Price may vary.

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Loperamide volume of distribution

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What is Loperamide

One of the long-acting synthetic antidiarrheals; it is not significantly absorbed from the gut, and has no effect on the adrenergic system or central nervous system, but may antagonize histamine and interfere with acetylcholine release locally.

Loperamide mechanism of action

iIn vitro/i and animal studies show that Loperamide acts by slowing intestinal motility and by affecting water and electrolyte movement through the bowel. Loperamide inhibits peristaltic activity by a direct effect on the circular and longitudinal muscles of the intestinal wall. It is a non-selective calcium channel blocker and binds to opioid mu-receptors. Evidence also suggests that at higher concentrations it binds to calmodulin.

Dosage forms of Loperamide

FormRouteStrength
Capsule, liquid filledoral2 mg/1
Tabletoral2 mg/1
Solutionoral.2 mg
Prescription Generics

true

International Brands

7 Select Anti Diarrheal

Synonyms

Loperamid Loperamida

Manufacturers

7 Eleven

CAS number

53179-11-6

UNII

6X9OC3H4II

State

solid

Affected organisms

Humans and other mammals

Indication of Loperamide

For the control and symptomatic relief of acute nonspecific diarrhea and of chronic diarrhea associated with inflammatory bowel disease or gastroenteritis. Also used for reducing the volume of discharge from ileostomies.

Toxicity of Loperamide

Oral, mouse: LDsub50/sub = 105 mg/kg. Symptoms of overdose include constipation, drowsiness, lethargy, and nausea.

RX24 Drugs Disclaimer: before buying a Loperamide on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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