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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Malathion

Malathion 0.5% lotion



* price without discount in nearest pharmacy. Price may vary.

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What is Malathion

Malathion is a parasympathomimetic organophosphate compound that is used as an insecticide for the treatment of head lice. Malathion is an irreversible cholinesterase inhibitor and has low human toxicity.

Malathion mechanism of action

Malathion is a nonsystemic, wide-spectrum organophosphate insecticide. It inhibits acetylcholinesterase activity of most eukaryotes. Malathion is toxic to aquatic organisms, but has a relatively low toxicity for birds and mammals. The major metabolites of malathion are mono- and di-carboxylic acid derivatives, and malaoxon is a minor metabolite. However, it is malaoxon that is the strongest cholinesterase inhibitor. Cholinesterases catalyze the hydrolysis of the neurotransmitter acetylcholine into choline and acetic acid, a reaction necessary to allow a cholinergic neuron to return to its resting state after activation. Because of its essential function, chemicals that interfere with the action of cholinesterase are potent neurotoxins, causing muscle spasms and ultimately death.

Dosage forms of Malathion

Form Route Strength
Lotion topical 5 mg/mL
Lotion topical .0005 g/mL
Lotion topical .005 g/mL
Prescription Generics


International Brands



((Dimethoxyphosphinothioyl)thio)butanedioic acid diethyl ester Carbophos


Taro Pharmaceuticals U.S.A., Inc.

CAS number






Affected organisms

Head lice

Indication of Malathion

For patients infected with Pediculus humanus capitis (head lice and their ova) of the scalp hair.

Toxicity of Malathion

Malathion is slightly toxic via the oral route, with reported oral LDsub50/sub values of 1000 mg/kg to greater than 10,000 mg/kg in the rat. It is also slightly toxic via the dermal route, with reported dermal LDsub50/sub values of greater than 4000 mg/kg in rats. Moderate poisoning can result in chest tightness, difficulty breathing, bradycardia, tachycardia, tremor/ataxia, blurred vision, and confusion. Severe, life-threatening signs include coma, seizures, respiratory arrest, and paralysis. Malathion may also be irritating to the skin and eyes.

RX24 Drugs Disclaimer: before buying a Malathion on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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