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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Emverm

$389.451 chewable/100mg
Price with discount in nearest pharmacy. Price may vary.

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Mebendazole volume of distribution

Following the intravenous administration of a tracer dose (1.7 microgram) of [3H]-mebendazole to a man, an elimination half-life of 1.16 h was observed and the volume of distribution was calculated to be 2.03 l/kg. After oral administration of the same dose, an elimination half-life of 0.74 h was observed.

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What is Mebendazole

A benzimidazole that acts by interfering with carbohydrate metabolism and inhibiting polymerization of microtubules.

Mebendazole mechanism of action

Mebendazole causes degenerative alterations in the tegument and intestinal cells of the worm by binding to the colchicine-sensitive site of tubulin, thus inhibiting its polymerization or assembly into microtubules. The loss of the cytoplasmic microtubules leads to impaired uptake of glucose by the larval and adult stages of the susceptible parasites, and depletes their glycogen stores. Degenerative changes in the endoplasmic reticulum, the mitochondria of the germinal layer, and the subsequent release of lysosomes result in decreased production of adenosine triphosphate (ATP), which is the energy required for the survival of the helminth. Due to diminished energy production, the parasite is immobilized and eventually dies.

Dosage forms of Mebendazole

Vermox100mg6 Tablet$41.00
Vermox Suspension100mg/5mL30mL Suspension$42.50
Vermox Suspension100mg/5mL60mL Suspension$55.00
Vermox Suspension100mg/5mL90mL Suspension$67.00
Mebendazole100mg30 Tablet$37.00

Prescription Generics


International Brands



(5-benzoyl-1H-benzimidazol-2-yl)-carbamic acid methyl ester MBDZ


Amedra Pharmaceuticals LLC

CAS number






Affected organisms

Helminthic Microorganisms

Indication of Mebendazole

For the treatment of iEnterobius vermicularis /i (pinworm), iTrichuris trichiura /i (whipworm), iAscaris lumbricoides /i (common roundworm), iAncylostoma duodenale /i (common hookworm), iNecator americanus /i (American hookworm) in single or mixed infections.

Toxicity of Mebendazole

Acute oral toxicity (LD sub50 /sub): 620 mg/kg (Mouse). Symptoms of overdose include elevated liver enzymes, headaches, hair loss, low levels of white blood cells (neutropenia), fever, and itching.

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