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Price of Mefloquine
Mefloquine hcl 250 mg tablet
* price without discount in nearest pharmacy. Price may vary.
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Mefloquine volume of distribution
* 20 L/kg (healthy adults)
What is Mefloquine
A phospholipid-interacting antimalarial drug (antimalarials). It is very effective against plasmodium falciparum with very few side effects. (PubChem)
Mefloquine mechanism of action
Mefloquine has been found to produce swelling of the i Plasmodium falciparum /i food vacuoles. It may act by forming toxic complexes with free heme that damage membranes and interact with other plasmodial components.
Dosage forms of Mefloquine
Lariam Tab 250mg
Hoffmann La Roche Limited
Indication of Mefloquine
For the treatment of mild to moderate acute malaria caused by Mefloquineuine-susceptible strains of i Plasmodium falciparum /i (both chloroquine-susceptible and resistant strains) or by i Plasmodium vivax /i . Also for the prophylaxis of i Plasmodium falciparum /i and i Plasmodium vivax /i malaria infections, including prophylaxis of chloroquine-resistant strains of i Plasmodium falciparum /i .
Toxicity of Mefloquine
Oral, rat: LD sub 50 /sub = 880 mg/kg. Symptoms of overdose include nausea, vomiting, and weight loss.
Disclaimer: before buying a Mefloquine on prescription, consult your health care provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.