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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Meropenem

Merrem 500 mg Solution Vial

$48.79

vial

* price without discount in nearest pharmacy. Price may vary.

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What is Meropenem

Meropenem is a broad-spectrum carbapenem antibiotic. It is active against Gram-positive and Gram-negative bacteria. Meropenem exerts its action by penetrating bacterial cells readily and interfering with the synthesis of vital cell wall components, which leads to cell death.

Meropenem mechanism of action

The bactericidal activity of meropenem results from the inhibition of cell wall synthesis. Meropenem readily penetrates the cell wall of most Gram-positive and Gram-negative bacteria to reach penicillin-binding- protein (PBP) targets. Its strongest affinities are toward PBPs 2, 3 and 4 of iEscherichia coli/i and iPseudomonas aeruginosa/i; and PBPs 1, 2 and 4 of iStaphylococcus aureus/i.

Dosage forms of Meropenem

FormRouteStrength
Injection, powder, for solutionintravenous1 g/20mL
Injection, powder, for solutionintravenous1 g/30mL
Injection, powder, for solutionintravenous500 mg/10mL
Prescription Generics

true

International Brands

Meropenem

Synonyms

(1R,5S,6S)-2-((3S,5S)-5-DIMETHYLAMINOCARBONYLPYRROLIDIN-3-ylthio)-6-((R)-1-hydroxyethyl)-1-methylcarbapen-2-em-3-carboxylic acid (4R,5S,6S)-3-{((3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl)thio}-6-((1R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid

Manufacturers

Gland Pharma Limited

CAS number

119478-56-7

UNII

FV9J3JU8B1

State

solid

Affected organisms

Enteric bacteria and other eubacteria

Indication of Meropenem

For use as single agent therapy for the treatment of the following infections when caused by susceptible isolates of the designated microorganisms: bcomplicated skin and skin structure infections/b due to iStaphylococcus aureus/i (b-lactamase and non-b-lactamase producing, methicillin-susceptible isolates only), iStreptococcus pyogenes/i, iStreptococcus agalactiae/i, viridans group streptococci, iEnterococcus faecalis/i (excluding vancomycin-resistant isolates), iPseudomonas aeruginosa/i, iEscherichia coli/i, iProteus mirabilis/i, iBacteroides fragilis/i and iPeptostreptococcus/i species; bcomplicated appendicitis and peritonitis/b caused by viridans group streptococci, iEscherichia coli/i, iKlebsiella pneumoniae/i, iPseudomonas aeruginosa/i, iBacteroides fragilis/i, iB. thetaiotaomicron/i, and iPeptostreptococcus/i species. Also for use in the treatment of bacterial meningitis caused by iStreptococcus pneumoniae/i, iHaemophilus influenzae/i (b-lactamase and non-b-lactamase-producing isolates), and iNeisseria meningitidis/i.

Toxicity of Meropenem

In mice and rats, large intravenous doses of meropenem (2200-4000 mg/kg) have been associated with ataxia, dyspnea, convulsions, and mortalities.

RX24 Drugs Disclaimer: before buying a Meropenem on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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