Save up -80% on Methyl aminolevulinate
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Methyl aminolevulinate
Metvixia 16.8% cream
|price without discount in nearest pharmacy. Price may vary.|
We offer free Methyl aminolevulinate coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Methyl aminolevulinate every time. What are you waiting for? Claim your prescription drug card now!
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Methyl aminolevulinate volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Methyl aminolevulinate
Methyl aminolevulinate is a prodrug that is metabolised to Protoporphyrin IX (a photosensitizer) used in photodynamic therapy.
Methyl aminolevulinate mechanism of action
Photosensitization following application of methyl aminolevulinate cream occurs through the metabolic conversion of methyl aminolevulinate (prodrug) to photoactive porphyrins (PAP), which accumulates in the skin lesions to which the cream has been applied. When exposed to light of appropriate wavelength and energy, the accumulated photoactive porphyrins produce a photodynamic reaction, resulting in a cytotoxic process dependent upon the simultaneous presence of oxygen. The absorption of light results in an excited state of porphyrin molecules, and subsequent spin transfer from photoactive porphyrins to molecular oxygen generates singlet oxygen, which can further react to form superoxide and hydroxyl radicals.
Dosage forms of Methyl aminolevulinate
5-Aminolevulinic acid methyl ester Aminolevulinic acid methyl ester
Galderma Canada Inc
Humans and other mammals
Indication of Methyl aminolevulinate
For topical use, in combination with 570 to 670 nm wavelength red light illumination, in the treatment of non-hyperkeratotic actinic keratoses of the face and scalp in immunocompetent patients when used in conjunction with lesion preparation (debridement using a sharp dermal curette).
Toxicity of Methyl aminolevulinate
The severity of local phototoxic reactions such as erythema, pain and burning sensation may increase in case of prolonged application time or very high light intensity.
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