Save up -80% on Mexiletine

Note: this is a drug discount program, not an insurance plan.

RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Mexiletine

Mexiletine 150 mg capsule

$1.11

capsule

* price without discount in nearest pharmacy. Price may vary.

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Mexiletine volume of distribution

* 5 to 7 L/lg

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What is Mexiletine

Antiarrhythmic agent pharmacologically similar to lidocaine. It may have some anticonvulsant properties.

Mexiletine mechanism of action

Mexiletine, like lidocaine, inhibits the inward sodium current required for the initiation and conduction of impulses, thus reducing the rate of rise of the action potential, Phase 0. It achieves this reduced sodium current by inhibiting sodium channels. Mexiletine decreases the effective refractory period (ERP) in Purkinje fibers in the heart. The decrease in ERP is of lesser magnitude than the decrease in action potential duration (APD), which results in an increase in the ERP/APD ratio. It does not significantly affect resting membrane potential or sinus node automaticity, left ventricular function, systolic arterial blood pressure, atrioventricular (AV) conduction velocity, or QRS or QT intervals

Dosage forms of Mexiletine

FormRouteStrength
Capsuleoral100 mg
Capsuleoral200 mg
Capsuleoral150 mg/1
Prescription Generics

false

International Brands

Alti-mexiletine

Synonyms

(+-)-1-(2,6-Dimethylphenoxy)propan-2-amine (2RS)-1-(2,6-dimethylphenoxy)-2-aminopropane

Manufacturers

Altimed Pharma Inc.

CAS number

31828-71-4

UNII

1U511HHV4Z

State

solid

Affected organisms

Humans and other mammals

Indication of Mexiletine

For the treatment of ventricular tachycardia and symptomatic premature ventricular beats, and prevention of ventricular fibrillation.

Toxicity of Mexiletine

Symptoms of overdose include nausea, hypotension, sinus bradycardia, paresthesia, seizures, bundle branch block, AV heart block, asystole, ventricular tachyarrythmia, including ventricular fibrillation, cardiovascular collapse, and coma.

RX24 Drugs Disclaimer: before buying a Mexiletine on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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