Save up -80% on Milnacipran

Note: this is a drug discount program, not an insurance plan.
RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Savella

$63.3660 tablets/50 mg
price without discount in nearest pharmacy. Price may vary.

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We offer free Savella coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Milnacipran every time. What are you waiting for? Claim your prescription drug card now!

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Milnacipran volume of distribution

The volume of distribution of Milnacipran is about 5 litre/kg with a total clearance of about 40 litre/hour. Renal and non-renal clearances are equivalent. Milnacipran is metabolized mainly by conjugation (Glucoronisation).

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2018 Statistics

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Discount Cards 16,000+

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Clients Benefit 29%

savings

Total savings $4,735,080

What is Milnacipran

Milnacipran is an antidepressant of the serotonin-norepinephrine reuptake inhibitor class. It more potently inhibits norepinephrine uptake than serotonin. It is provided as a racemic mixture. FDA approved in January 2009.

Milnacipran mechanism of action

Milnacipran inhibits norepinephrine and serotonin reuptake in a 3:1 ratio, in practical use this means a balanced (equal) action upon both transmitters. The serotonin reuptake inhibition is likely to improve depression, while the norepinephrine reuptake inihibition probably improves chronic pain. Milnacipran exerts no significant actions on postynaptic H1, alpha-1, D1, D2, and muscarinic receptors, as well as on benzodiazepine/opiate binding sites.[Wikipedia]

Dosage forms of Milnacipran

DrugDosageQuantityPrice
Milnacipran50mg100 Capsule$148.00
Savella50mg56 Capsule$106.00

Prescription Generics

true

International Brands

Milnacipran Hydrochloride

Synonyms

(-)-milnacipran Midalcipran

Manufacturers

Ranbaxy Pharmaceuticals Inc.

CAS number

92623-85-3

UNII

G56VK1HF36

State

solid

Affected organisms

Humans and other mammals

Indication of Milnacipran

Milnacipran is used to treat moderate to severe clinical depression but this indication is not yet FDA-approved in the USA. Milnacipran is labelled for the treatment of fibromyalgia pain.

Toxicity of Milnacipran

LD50, oral, rat: 213 mg/kg. The most frequently occurring adverse reactions ( 5% and greater than placebo) were nausea, headache, constipation, dizziness, insomnia, hot flush, hyperhidrosis, vomiting, palpitations, heart rate increased, dry mouth, and hypertension.

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What is a Savella?

Savella is used to treat pain caused by a condition called fibromyalgia, which affects the muscles, tendons, ligaments, and supporting tissues. An antidepressant from the group of selective serotonin and norepinephrine reuptake inhibitors. Approved for the treatment of fibromyalgia in adults.

Savella contains milnacipran consisting of two enantiomers: destromylnacipran and levomilnacipran. Take this medication by mouth with or without food, usually 2 times a day or as directed by a doctor. This drug is an inhibitor of serotonin and norepinephrine reuptake (IOSP), which works by helping to restore the balance of certain natural substances in the brain (neurotransmitters).