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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Milrinone

Milrinone lact 10 mg/10 ml vial

$1.31

ml

* price without discount in nearest pharmacy. Price may vary.

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Milrinone volume of distribution

* 0.38 liters/kg (intravenous injections of 12.5 mcg/kg to 125 mcg/kg to congestive heart failure patients) * 0.45 liters/kg (intravenous infusions of 0.20 mcg/kg/min to 0.70 mcg/kg/min to congestive heart failure patients)

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What is Milrinone

A positive inotropic cardiotonic agent with vasodilator properties. It inhibits cAMP phosphodiesterase activity in myocardium and vascular smooth muscle. Milrinone is a derivative of amrinone and has 20-30 times the ionotropic potency of amrinone.

Milrinone mechanism of action

Milrinone inhibits erythrocyte phosphodiesterase, resulting in an increase in erythrocyte cAMP activity. Subsequently, the erythrocyte membrane becomes more resistant to deformity. Along with erythrocyte activity, Milrinone also decreases blood viscosity by reducing plasma fibrinogen concentrations and increasing fibrinolytic activity.

Dosage forms of Milrinone

FormRouteStrength
Injectionintravenous1 mg/mL
Injection, solutionintravenous1 mg/mL
Injection, solutionintravenous10 mg/10mL
Prescription Generics

true

International Brands

Apo-milrinone Injectable

Synonyms

1,6-Dihydro-2-methyl-6-oxo(3,4′-bipyridine)-5-carbonitrile Milrinona

Manufacturers

Apotex Inc

CAS number

78415-72-2

UNII

JU9YAX04C7

State

solid

Affected organisms

Humans and other mammals

Indication of Milrinone

Indicated for the treatment of congestive heart failure.

Toxicity of Milrinone

LD sub 50 /sub = 0.3 mg/L in rats

RX24 Drugs Disclaimer: before buying a Milrinone on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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