Save up -80% on Mipomersen

Note: this is a drug discount program, not an insurance plan.
RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Kynamro

$27,5334 kits (1 syringe) 200mg/ml
price without discount in nearest pharmacy. Price may vary.

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We offer free Mipomersen coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Mipomersen every time. What are you waiting for? Claim your prescription drug card now!

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Mipomersen volume of distribution

The volume of distribution for mipomersen was not quantified.

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About RX24Drugs

2018 Statistics

discount card

Discount Cards 16,000+

benefit

Clients Benefit 29%

savings

Total savings $4,735,080

What is Mipomersen

Mipomersen sodium, which was known as the investigational drug, isis-301012, is the salt form of a synthetic phosphorothioate oligonucleotide. Mipomersen sodium prevents the formation of apo B-100, resulting in a decrease in the levels of apolipoprotein B (apo B), low density lipoprotein (LDL), and total cholesterol. Mipomersen is indicated in patients with homozygous familial hypercholesterolemia as an adjunct to diet and other lipid-lowering medications. It is marketed under the brand name Kynamro in the United States, and the FDA label includes a black box warning of hepatoxicity. Specifically, elevations in the liver enzymes, i.e. transaminases, and in liver fat (hepatic steatosis) have been reported. Due to this serious risk of liver toxicity, mipomersen sodium is only available to patients under the restricted program called Kynamro Risk Evaluation and Mitigation Strategy program.

Mipomersen mechanism of action

Mipomersen binds to the mRNA that codes for apoB-100. This binding leads to double-stranded RNA, which is degraded by RNase H and prevents translation of the mRNA to form the apo B-100 protein.

Dosage forms of Mipomersen

FormRouteStrength
Injection, solutionsubcutaneous200 mg/mL

Prescription Generics

false

International Brands

Kynamro

Synonyms

Manufacturers

Kastle Therapeutics Llc

CAS number

1000120-98-8

UNII

9GJ8S4GU0M

State

liquid

Affected organisms

Humans and other mammals

Indication of Mipomersen

Used in patients with homozygous familial hypercholesterolemia as an adjunct to diet and other lipid-lowering medications.

Toxicity of Mipomersen

The FDA label includes a black box warning of mipomersem induced hepatoxicity. Other less serious adverse effects include nausea, headache, fatigue, local injection site reactions, and flu-like symptoms.

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Mipomersen on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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