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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Mirabegron


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Mirabegron volume of distribution

Vd, steady state, IV dose = 1670 L. This high value suggests that mirabegron is extensively distributed in the body.

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What is Mirabegron

Mirabegron is a beta-3 adrenergic receptor agonist for the management of overactive bladder. It is an alternative to antimuscarinic drugs for this indication. FDA approved on June 28, 2012.

Mirabegron mechanism of action

Mirabegron is a potent and selective agonist for beta-3 adrenergic receptors. Once beta-3 receptors are activated, the detrusor smooth muscle relaxes to allow for a larger bladder capacity. At higher doses (200 mg), there is a potential for mirabegron to activate beta-1 and beta-2 adrenergic receptors.

Dosage forms of Mirabegron

Prolonged-release tabletOral use25 mg
Prolonged-release tabletOral use50 mg
Tablet (extended-release)oral25 mg
Prescription Generics


International Brands





Astellas Pharma US, Inc.

CAS number






Affected organisms

Humans and other mammals

Indication of Mirabegron

Mirabegron is a beta-3 adrenergic agonist indicated for the treatment of overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency.

Toxicity of Mirabegron

Most commonly reported adverse reactions ( 2% and placebo) were hypertension, nasopharyngitis, urinary tract infection and headache

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