Save up -80% on Mitoxantrone

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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Mitoxantrone

Mitoxantrone 25 mg/12.5 ml vial



* price without discount in nearest pharmacy. Price may vary.

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Mitoxantrone volume of distribution

* 1000 L/m2

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What is Mitoxantrone

An anthracenedione-derived antineoplastic agent.

Mitoxantrone mechanism of action

Mitoxantrone, a DNA-reactive agent that intercalates into deoxyribonucleic acid (DNA) through hydrogen bonding, causes crosslinks and strand breaks. Mitoxantrone also interferes with ribonucleic acid (RNA) and is a potent inhibitor of topoisomerase II, an enzyme responsible for uncoiling and repairing damaged DNA. It has a cytocidal effect on both proliferating and nonproliferating cultured human cells, suggesting lack of cell cycle phase specificity.

Dosage forms of Mitoxantrone

Injection, solution, concentrateintravenous2 mg/mL
Injection, solutionintravenous2 mg/mL
Solutionintravenous2 mg
Prescription Generics


International Brands



1,4-DIHYDROXY-5,8-bis({2-((2-hydroxyethyl)amino)ethyl}amino)-9,10-anthracenedione Mitoxantrona


Teva Parenteral Medicines, Inc

CAS number






Affected organisms

Humans and other mammals

Indication of Mitoxantrone

For the treatment of secondary (chronic) progressive, progressive relapsing, or worsening relapsing-remitting multiple sclerosis

Toxicity of Mitoxantrone

Severe leukopenia with infection.

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