Save up -80% on Mitoxantrone
Note: this is a drug discount program, not an insurance plan.
2018 Price of Mitoxantrone
Mitoxantrone 25 mg/12.5 ml vial
* price without discount in nearest pharmacy. Price may vary.
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Mitoxantrone volume of distribution
* 1000 L/m2
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Mitoxantrone
An anthracenedione-derived antineoplastic agent.
Mitoxantrone mechanism of action
Mitoxantrone, a DNA-reactive agent that intercalates into deoxyribonucleic acid (DNA) through hydrogen bonding, causes crosslinks and strand breaks. Mitoxantrone also interferes with ribonucleic acid (RNA) and is a potent inhibitor of topoisomerase II, an enzyme responsible for uncoiling and repairing damaged DNA. It has a cytocidal effect on both proliferating and nonproliferating cultured human cells, suggesting lack of cell cycle phase specificity.
Dosage forms of Mitoxantrone
|Injection, solution, concentrate||intravenous||2 mg/mL|
|Injection, solution||intravenous||2 mg/mL|
Teva Parenteral Medicines, Inc
Humans and other mammals
Toxicity of Mitoxantrone
Severe leukopenia with infection.
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