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2018 Price of Monobenzone
Hydroquinone mono benzyl ether
g
* price without discount in nearest pharmacy. Price may vary.
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Monobenzone volume of distribution
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What is Monobenzone
Monobenzone is the monobenzyl ether of hydroquinone used medically for depigmentation. Monobenzone occurs as a white, almost tasteless crystalline powder, soluble in alcohol and practically insoluble in water. The topical application of monobenzone in animals increases the excretion of melanin from the melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans. Monobenzone may cause destruction of melanocytes and permanent depigmentation.
Monobenzone mechanism of action
Monobenzone is a depigmenting agent whose mechanism of action is not fully understood. The topical application of monobenzone in animals, increases the excretion of melanin from the melanocytes. The same action is thought to be responsible for the depigmenting effect of the drug in humans. Monobenzone may cause destruction of melanocytes and permanent depigmentation. This effect is erratic and may take one to four months to occur while existing melanin is lost with normal sloughing of the stratum corneum. Hyperpigmented skin appears to fade more rapidly than does normal skin, and exposure to sunlight reduces the depigmenting effect of the drug. The histology of the skin after depigmentation with topical monobenzone is the same as that seen in vitiligo; the epidermis is normal except for the absence of identifiable melanocytes.
Dosage forms of Monobenzone
| Form | Route | Strength |
|---|---|---|
| Cream | topical | 20 % |
Prescription Generics
false
International Brands
Benoquin Crm 20%
Synonyms
4-(Benzyloxy)phenol 4-(Benzyloxyl)phenol
Manufacturers
Valeant Canada Lp Valeant Canada S.E.C.
CAS number
103-16-2
UNII
9L2KA76MG5
State
solid
Affected organisms
Humans and other mammals
Indication of Monobenzone
Used topically to treat the loss of skin color (vitiligo).
Toxicity of Monobenzone
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