Save up -80% on Montelukast
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2018 Price of Montelukast
Singulair 10 mg tablet
* price without discount in nearest pharmacy. Price may vary.
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Montelukast volume of distribution
* 8 to 11 L
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Montelukast
Montelukast is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. It is usually administered orally. Montelukast blocks the action of leukotriene D4 on the cysteinyl leukotriene receptor CysLT1 in the lungs and bronchial tubes by binding to it. This reduces the bronchoconstriction otherwise caused by the leukotriene, and results in less inflammation. Because of its method of operation, it is not useful for the treatment of acute asthma attacks. Again because of its very specific locus of operation, it does not interact with other allergy medications such as theophylline. Montelukast is marketed in United States and many other countries by Merck amp; Co. with the brand name Singulair. It is available as oral tablets, chewable tablets, and oral granules. In India and other countries, it is also marketed under the brand name Montair reg;, produced by Indian company Cipla.
Montelukast mechanism of action
Montelukast selectively antagonizes leukotriene D sub4 /sub (LTD sub4 /sub) at the cysteinyl leukotriene receptor, CysLT sub1 /sub, in the human airway. Montelukast inhibits the actions of LTD sub4 /sub at the CysLT sub1 /sub receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus.
Dosage forms of Montelukast
|Tablet, chewable||oral||4 mg/1|
|Tablet, chewable||oral||5 mg/1|
|Tablet, film coated||oral||10 mg/1|
Accel-montelukast Sodium Tablets
(R-(e))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid 1-((((1 R)-1-(3-((1e)-2-(7-chloro-2-Quinolinyl)ethenyl) phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)sulfanyl)methyl)cyclopropaneacetic acid
Accel Pharma Inc
Humans and other mammals
Indication of Montelukast
For the treatment of asthma
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