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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Vigamox

$33.351 eye dropper (3ml) 0.5%
price without discount in nearest pharmacy. Price may vary.

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Moxifloxacin volume of distribution

Following intravenous administration, the half life of elimination, the volume of distribution at steady state and the area under the curve were 3.29 h, 0.94 l/kg and 24.72 microg x h/ml, respectively. After intramuscular and subcutaneous administration of moxifloxacin at the same dose, the peak plasma concentrations were 2.41 and 2.20 microg/ml and were obtained at 1.54 and 1.59 h, respectively. The systemic bioavailabilities were 87.19 and 75.94%, respectively. The in vitro plasma protein binding of moxifloxacin in plasma of calves was 27%.

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Total savings $4,735,080

What is Moxifloxacin

Moxifloxacin is a synthetic fluoroquinolone antibiotic agent. Bayer AG developed the drug (initially called BAY 12-8039) and it is marketed worldwide (as the hydrochloride) under the brand name Avelox (in some countries also Avalox) for oral treatment.

Moxifloxacin mechanism of action

The bactericidal action of moxifloxacin results from inhibition of the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV. DNA gyrase is an essential enzyme that is involved in the replication, transcription and repair of bacterial DNA. Topoisomerase IV is an enzyme known to play a key role in the partitioning of the chromosomal DNA during bacterial cell division.

Dosage forms of Moxifloxacin

DrugDosageQuantityPrice
Vigamox0.50%5mL Eye drops$44.00
Avelox400mg14 Tablet$102.00
Avelox400mg28 Tablet$197.00
Moxifloxacin0.50%3mL Eye drops$36.00
Moxifloxacin0.50%9mL Eye drops$79.00
Moxifloxacin400mg30 Tablet$114.00
Moxifloxacin400mg100 Tablet$336.00

Prescription Generics

false

International Brands

Act Moxifloxacin

Synonyms

1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-((4as,7as)-octahydro-6H-pyrrolo(3,4-b)pyridin-6-yl)-4-oxo-3-quinolinecarboxylic acid

Manufacturers

Actavis Pharma Company

CAS number

151096-09-2

UNII

U188XYD42P

State

solid

Affected organisms

Enteric bacteria and other eubacteria

Indication of Moxifloxacin

For the treatment of sinus and lung infections such as sinusitis, pneumonia, and secondary infections in chronic bronchitis. Also for the treatment of bacterial conjunctivitis (pinkeye).

Toxicity of Moxifloxacin

Symptoms of overdose include CNS and gastrointestinal effects such as decreased activity, somnolence, tremor, convulsions, vomiting, and diarrhea. The minimal lethal intravenous dose in mice and rats is 100 mg/kg.

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Moxifloxacin on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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What is a Vigamox?

Vigamox eye drops contain moxifloxacin), a fluoroquinolone antibiotic used to combat bacterial infections of the eye and to treat bacterial conjunctivitis in the eyes. Vigamox will not treat a viral or fungal infection of the eye. This medicine is intended to treat only bacterial infections.

Do not use Vigamox if you have a viral or fungal infection in the eye. It is used to treat infections caused only by bacteria. Do not use this medicine if you have had an allergic reaction to it or other similar medicines in the past. Drugs available in the world Vigamox , Levofloxacin Ophthalmic (Quixin), Levofloxacin (Levaquin), Lomefloxacin (Maxaquin), Sparfloxacin (Zagam), Trovafloxacin (Trovan) and Moxifloxacin (Avelox).