Save up -80% on Mupirocin
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2018 Price of Mupirocin
Mupirocin 2% ointment
* price without discount in nearest pharmacy. Price may vary.
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Mupirocin volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Mupirocin
Mupirocin (pseudomonic acid A, or Bactroban or Centany) is an antibiotic originally isolated from Pseudomonas fluorescens. It is used topically, and is primarily effective against Gram-positive bacteria. Mupirocin is bacteriostatic at low concentrations and bactericidal at high concentrations. Mupirocin has a unique mechanism of action, which is selective binding to bacterial isoleucyl-tRNA synthetase, which halts the incorporation of isoleucine into bacterial proteins. Because this mechanism of action is not shared with any other antibiotic, mupirocin has few problems of antibiotic cross-resistance.
Mupirocin mechanism of action
Mupirocin reversibly binds to bacterial isoleucyl-tRNA synthetase, an enzyme which promotes the conversion of isoleucine and tRNA to isoleucyl-tRNA. Prevention of this enzymes from functioning properly results in the inhibition of bacterial protein and RNA synthesis.
Dosage forms of Mupirocin
9-((E)-4-((2S,3R,4R,5S)-3,4-dihydroxy-5-(((2S,3S)-3- ((2S,3S)-3-hydroxybutan-2-yl)oxiran-2-yl)methyl) oxan-2-yl)-3-methylbut-2-enoyl)oxynonanoic acid Bactroban
Glaxosmithkline Consumer Healthcare Inc.
Enteric bacteria and other eubacteria
Indication of Mupirocin
For the treatment of iStaphylococci /i nasal carriers.
Toxicity of Mupirocin
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