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Price of Nabumetone
Nabumetone 500 mg tablet
* price without discount in nearest pharmacy. Price may vary.
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Nabumetone volume of distribution
What is Nabumetone
Nabumetone is a nonsteroidal anti-inflammatory drug (NSAID) of the arylalkanoic acid family (which includes diclofenac). Marketed under the brand name Relafen, it has been shown to have a slightly lower risk of gastrointestinal side effects than most other non-selective NSAIDs.
Nabumetone mechanism of action
The parent compound is a prodrug, which undergoes hepatic biotransformation to the active component, 6-methoxy-2-naphthylacetic acid (6MNA), that is a potent inhibitor of prostaglandin synthesis, most likely through binding to the COX-2 and COX-1 receptors.
Dosage forms of Nabumetone
Humans and other mammals
Indication of Nabumetone
For acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.
Toxicity of Nabumetone
The one overdose occurred in a 17-year-old female patient who had a history of abdominal pain and was hospitalized for increased abdominal pain following ingestion of 30 nabumetone tablets (15 grams total). Stools were negative for occult blood and there was no fall in serum hemoglobin concentration. The patient had no other symptoms.
Disclaimer: before buying a Nabumetone on prescription, consult your health care provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.