Save up -80% on Nalidixic Acid

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Nalidixic Acid

Nalidixic acid powder

$7.2

g

* price without discount in nearest pharmacy. Price may vary.

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Nalidixic Acid volume of distribution

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What is Nalidixic Acid

A synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.

Nalidixic Acid mechanism of action

Evidence exists for Nalidixic acid that its active metabolite, hydroxynalidixic acid, binds strongly, but reversibly, to DNA, interfering with synthesis of RNA and, consequently, with protein synthesis.

Dosage forms of Nalidixic Acid

FormRouteStrength
Tabletoral500 mg
Prescription Generics

false

International Brands

Neggram

Synonyms

1-Aethyl-7-methyl-1,8-naphthyridin-4-on-3-karbonsaeure 1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid

Manufacturers

Sanofi Aventis Canada Inc

CAS number

389-08-2

UNII

3B91HWA56M

State

solid

Affected organisms

Enteric bacteria and other eubacteria

Indication of Nalidixic Acid

For the treatment of urinary tract infections caused by susceptible gram-negative microorganisms, including the majority of iE. Coli/i, iEnterobacter/i species, iKlebsiella/i species, and iProteus/i species.

Toxicity of Nalidixic Acid

ORAL (LDsub50/sub): Acute: 1160 mg/kg (Rat). 572 mg/kg (Mouse). Toxic psychosis, convulsions, increased intracranial pressure, or metabolic acidosis may occur in patients taking more than the recommended dosage. Vomiting, nausea, and lethargy may also occur following overdosage.

RX24 Drugs Disclaimer: before buying a Nalidixic Acid on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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