Save up -80% on Nicardipine

Note: this is a drug discount program, not an insurance plan.
RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Cardene

$36.7760 capsules/20mg
price without discount in nearest pharmacy. Price may vary.

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We offer free Cardene coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Nicardipine every time. What are you waiting for? Claim your prescription drug card now!

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Nicardipine volume of distribution

Total plasma clearance (Cl) is 0.4 L/hr. kg, and the apparent volume of distribution (Vd) using a non-compartment model is 8.3 L/kg. The pharmacokinetics of Cardene I.V.

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2018 Statistics

discount card

Discount Cards 16,000+

benefit

Clients Benefit 29%

savings

Total savings $4,735,080

What is Nicardipine

A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.

Nicardipine mechanism of action

By deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum, nicardipine inhibits the influx of extracellular calcium across the myocardial and vascular smooth muscle cell membranes The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.

Dosage forms of Nicardipine

FormRouteStrength
Capsuleoral20 mg
Capsuleoral30 mg
Injection, solutionintravenous.1 mg/mL

Prescription Generics

false

International Brands

Cardene 20mg Capsules

Synonyms

Cardene Nicardipino

Manufacturers

Hoffmann La Roche Limited

CAS number

55985-32-5

UNII

CZ5312222S

State

solid

Affected organisms

Humans and other mammals

Indication of Nicardipine

Used for the management of patients with chronic stable angina and for the treatment of hypertension.

Toxicity of Nicardipine

Oral LD sub50 /sub Rat = 184 mg/kg, Oral LD sub50 /sub Mouse = 322 mg/kg

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Nicardipine on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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