Save up -80% on Nicotine

Note: this is a drug discount program, not an insurance plan.

RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

Pharmacists and Patients support.

2018 Price of Nicotine

Nicotrol cartridge inhaler

$1.28

each

* price without discount in nearest pharmacy. Price may vary.

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We offer free Nicotine coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your discount card in most local pharmacies to get a discount on Nicotine every time. What are you waiting for? Claim your prescription drug card now!

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Nicotine volume of distribution

* 2 to 3 L/kg

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What is Nicotine

Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.

Nicotine mechanism of action

Nicotine is a stimulant drug that acts as an agonist at nicotinic acetylcholine receptors. These are ionotropic receptors composed up of five homomeric or heteromeric subunits. In the brain, nicotine binds to nicotinic acetylcholine receptors on dopaminergic neurons in the cortico-limbic pathways. This causes the channel to open and allow conductance of multiple cations including sodium, calcium, and potassium. This leads to depolarization, which activates voltage-gated calcium channels and allows more calcium to enter the axon terminal. Calcium stimulates vesicle trafficking towards the plasma membrane and the release of dopamine into the synapse. Dopamine binding to its receptors is responsible the euphoric and addictive properties of nicotine. Nicotine also binds to nicotinic acetylcholine receptors on the chromaffin cells in the adrenal medulla. Binding opens the ion channel allowing influx of sodium, causing depolarization of the cell, which activates voltage-gated calcium channels. Calcium triggers the release of epinephrine from intracellular vesicles into the bloodstream, which causes vasoconstriction, increased blood pressure, increased heart rate, and increased blood sugar.

Dosage forms of Nicotine

DrugDosageQuantityPrice
Habitrol7mg7 Patches$33.46
Habitrol14mg7 Patches$33.46
Habitrol21mg7 Patches$33.46
Nicoderm7mg7 Patches$41.62
Nicoderm14mg7 Patches$41.62
Nicoderm21mg14 Patches$72.02
Nicorette Inhaler4mg42 Inhaler$58.00
Nicotine Polacrilex2mg120 Gum$45.00
Nicotine Polacrilex4mg120 Gum$45.00
Prescription Generics

false

International Brands

American Fare Nicotine Transdermal System

Synonyms

(+-)-3-(1-Methyl-2-pyrrolidinyl)pyridine (+-)-Nicotine

Manufacturers

Novartis Consumer Health, Inc.

CAS number

54-11-5

UNII

6M3C89ZY6R

State

liquid

Affected organisms

Humans and other mammals

Indication of Nicotine

For the relief of nicotine withdrawal symptoms and as an aid to smoking cessation.

Toxicity of Nicotine

Symptoms of overdose include nausea, abdominal pain, vomiting, diarrhea, diaphoresis, flushing, dizziness, disturbed hearing and vision, confusion, weakness, palpitations, altered respiration and hypotension. LD sub 50 /sub = 24 mg/kg (orally in mice).

RX24 Drugs Disclaimer: before buying a Nicotine on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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