Save up -80% on Nilotinib

Note: this is a drug discount program, not an insurance plan.
RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Tasigna

$12,6534 dose packs (28 capsules)/150 mg
price without discount in nearest pharmacy. Price may vary.

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We offer free Nilotinib coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your discount card in most local pharmacies to get a discount on Nilotinib every time. What are you waiting for? Claim your prescription drug card now!

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Nilotinib volume of distribution

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About RX24Drugs

2018 Statistics

discount card

Discount Cards 16,000+

benefit

Clients Benefit 29%

savings

Total savings $4,735,080

What is Nilotinib

Nilotinib, also known as AMN107, is a tyrosine kinase inhibitor under investigation as a possible treatment for chronic myelogenous leukemia (CML). In June 2006, a Phase I clinical trial found nilotinib has a relatively favorable safety profile and shows activity in cases of CML resistant to treatment with imatinib (Gleevec-reg;), another tyrosine kinase inhibitor currently used as a first-line treatment.[Wikipedia]

Nilotinib mechanism of action

Chronic myelogenous leukaemia (CML) is caused by the BCR-ABL oncogene. Nilotinib inhibits the tyrosine kinase activity of the BCR-ABL protein. Nilotinib fits into the ATP-binding site of the BCR-ABL protein with higher affinity than imatinib, over-riding resistance caused by mutations. The ability of AMN107 to inhibit TEL-platelet-derived growth factor receptor-beta (TEL-PDGFRbeta), which causes chronic myelomonocytic leukaemia, and FIP1-like-1-PDGFRalpha, which causes hypereosinophilic syndrome, suggests potential use of AMN107 for myeloproliferative diseases characterised by these kinase fusions (Stover et al, 2005; Weisberg et al, 2005). AMN107 also inhibits the c-Kit receptor kinase, including the D816V-mutated variant of KIT, at pharmacologically achievable concentrations, supporting potential utility in the treatment of mastocytosis, and gastrointestinal stromal tumours (Weisberg et al, 2005; von Bubnoff et al, 2005; Gleixner et al, 2006).

Dosage forms of Nilotinib

FormRouteStrength
Capsuleoral150 mg/1
Capsuleoral150 mg
Capsuleoral200 mg

Prescription Generics

false

International Brands

Tasigna

Synonyms

Nilotinibum

Manufacturers

Novartis Pharmaceuticals Canada Inc

CAS number

641571-10-0

UNII

F41401512X

State

solid

Affected organisms

Humans and other mammals

Indication of Nilotinib

For the potential treatment of various leukemias, including chronic myeloid leukemia (CML).

Toxicity of Nilotinib

RX24 Drugs Disclaimer: before buying a Nilotinib on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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