Save up -80% on Nimodipine

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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Nimodipine

$97.6960 capsules/30 mg
price without discount in nearest pharmacy. Price may vary.

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We offer free Nimodipine coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Nimodipine every time. What are you waiting for? Claim your prescription drug card now!

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About RX24Drugs

2018 Statistics

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Discount Cards 16,000+

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Clients Benefit 29%

savings

Total savings $4,735,080

What is Nimodipine

Nimodipine is a 1,4-dihydropyridine calcium channel blocker. It acts primarily on vascular smooth muscle cells by stabilizing voltage-gated L-type calcium channels in their inactive conformation. By inhibiting the influx of calcium in smooth muscle cells, nimodipine prevents calcium-dependent smooth muscle contraction and subsequent vasoconstriction. Compared to other calcium channel blocking agents, nimodipine exhibits greater effects on cerebral circulation than on peripheral circulation. Nimodipine is used to as an adjunct to improve the neurologic outcome following subarachnoid hemorrhage from ruptured intracranial aneurysm.

Nimodipine mechanism of action

Although the precise mechanism of action is not known, nimodipine blocks intracellular influx of calcium through voltage-dependent and receptor-operated slow calcium channels across the membranes of myocardial, vascular smooth muscle, and neuronal cells. Nimodipine binds specifically to L-type voltage-gated calcium channels. The inhibition of calcium ion transfer results in the inhibition of vascular smooth muscle contraction. Evidence suggests that the dilation of small cerebral resistance vessels, with a resultant increase in collateral circulation, and/or a direct effect involving the prevention of calcium overload in neurons may be responsible for nimodipine’s clinical effect in patients with subarachnoid hemorrhage.

Dosage forms of Nimodipine

FormRouteStrength
Capsuleoral30 mg/1
Capsule, liquid filledoral30 mg/1
Tabletoral30 mg

Prescription Generics

true

International Brands

Nimodipine

Synonyms

2,6-Dimethyl-4-(3′-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-beta-methoxyethyl ester 5-isopropyl ester BAY e 9736

Manufacturers

Caraco Pharmaceutical Laboratories, Ltd.

CAS number

66085-59-4

UNII

57WA9QZ5WH

State

solid

Affected organisms

Humans and other mammals

Indication of Nimodipine

For use as an adjunct to improve neurologic outcome following subarachnoid hemorrhage (SAH) from ruptured intracranial berry aneurysms by reducing the incidence and severity of ischemic deficits.

Toxicity of Nimodipine

Symptoms of overdosage would be expected to be related to cardiovascular effects such as excessive peripheral vasodilation with marked systemic hypotension.

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