Save up -80% on Nitrazepam
Note: this is a drug discount program, not an insurance plan.
2018 Price of Nitrazepam
Nitrazadon 5 mg Tablet
* price without discount in nearest pharmacy. Price may vary.
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Nitrazepam volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Nitrazepam
A benzodiazepine derivative used as an anticonvulsant and hypnotic.
Nitrazepam mechanism of action
Nitrazepam belongs to a group of medicines called benzodiazepines. It acts on benzodiazepine receptors in the brain which are associated with the GABA receptors causing an enhanced binding of GABA (gamma amino butyric acid) to GABAA receptors. GABA is a major inhibitory neurotransmitter in the brain, involved in inducing sleepiness, muscular relaxation and control of anxiety and fits, and slows down the central nervous system. The anticonvulsant properties of nitrazepam and other benzodiazepines may be in part or entirely due to binding to voltage-dependent sodium channels rather than benzodiazepine receptors. Sustained repetitive firing seems to be limited by benzodiazepines effect of slowing recovery of sodium channels from inactivation.
Dosage forms of Nitrazepam
Apo-nitrazepam Tablets BP
Humans and other mammals
Indication of Nitrazepam
Used to treat short-term sleeping problems (insomnia), such as difficulty falling asleep, frequent awakenings during the night, and early-morning awakening.
Toxicity of Nitrazepam
Nitrazepam is a drug which is very frequently involved in drug intoxication, including overdose. Nitrazepam overdose may result in stereotypical symptoms of benzodiazepine overdose including intoxication, impaired balance, slurred speech. In cases of severe overdose this may progress to a comatose state with the possibility of death.
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