Save up -80% on Nitroglycerin
Note: this is a drug discount program, not an insurance plan.
2018 Price of Nitroglycerin
Nitroglycerin er 9 mg capsule
* price without discount in nearest pharmacy. Price may vary.
We offer free Nitroglycerin coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your discount card in most local pharmacies to get a discount on Nitroglycerin every time. What are you waiting for? Claim your prescription drug card now!
Nitroglycerin volume of distribution
* 3 L/kg
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
Nitroglycerin mechanism of action
Similar to other nitrites and organic nitrates, nitroglycerin is converted to nitric oxide (NO), an active intermediate compound which activates the enzyme guanylate cyclase. This stimulates the synthesis of cyclic guanosine 3′,5′-monophosphate (cGMP) which then activates a series of protein kinase-dependent phosphorylations in the smooth muscle cells, eventually resulting in the dephosphorylation of the myosin light chain of the smooth muscle fiber. The subsequent release of calcium ions results in the relaxation of the smooth muscle cells and vasodilation.
Dosage forms of Nitroglycerin
1,2,3-Propanetrioltrinitrate 1,2,3-Propanetriyl nitrate
Humans and other mammals
Indication of Nitroglycerin
For the prevention of angina
Toxicity of Nitroglycerin
Increased intracranial pressure, with any or all of persistent throbbing headache, confusion, and moderate fever; Vertigo; Palpitations; Visual disturbances; Nausea and vomiting (possibly with colic and even bloody diarrhea); Syncope (especially in the upright posture); Air hunger and dyspnea, later followed by reduced ventilatory effort; Diaphoresis, with the skin either flushed or cold and clammy; Heart block and bradycardia; Paralysis; Coma; Seizures; Death.
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