Save up -80% on Ocriplasmin
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2018 Price of Ocriplasmin
* price without discount in nearest pharmacy. Price may vary.
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Ocriplasmin volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Ocriplasmin
Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced by recombinant DNA technology in a Pichia pastoris expression system. Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. Agent for pharmacologic vitreolysis; thrombolytic agent. FDA approved in October 17, 2012.
Ocriplasmin mechanism of action
Ocriplasmin has proteolytic activity against protein components of the vitreous body and the vitreoretinal interface (VRI) (e.g. laminin, fibronectin and collagen), thereby dissolving the protein matrix responsible for the vitreomacular adhesion (VMA).
Dosage forms of Ocriplasmin
|Concentrate for solution for injection||Intravitreal use||0.5 mg/0.2ml|
|Injection, solution||intravitreal||2.5 mg/mL|
Thrombo Genics Inc.
Humans and other mammals
Indication of Ocriplasmin
Ocriplasmin is a proteolytic enzyme indicated for the treatment for symptomatic vitreomacular adhesion.
Toxicity of Ocriplasmin
The most commonly reported reactions ( 5%) in patients treated with ocriplasmin were vitreous floaters, conjunctival hemorrhage, eye pain, photopsia, blurred vision, macular hole, reduced visual acuity, visual impairment, and retinal edema.
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