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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Ocriplasmin

$

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What is Ocriplasmin

Ocriplasmin is a recombinant truncated form of human plasmin with a molecular weight of 27.2 kDa produced by recombinant DNA technology in a Pichia pastoris expression system. Ocriplasmin is a protein made up of 249 amino acids and has two peptide chains. Agent for pharmacologic vitreolysis; thrombolytic agent. FDA approved in October 17, 2012.

Ocriplasmin mechanism of action

Ocriplasmin has proteolytic activity against protein components of the vitreous body and the vitreoretinal interface (VRI) (e.g. laminin, fibronectin and collagen), thereby dissolving the protein matrix responsible for the vitreomacular adhesion (VMA).

Dosage forms of Ocriplasmin

FormRouteStrength
Concentrate for solution for injectionIntravitreal use0.5 mg/0.2ml
Injection, solutionintravitreal2.5 mg/mL
Solutionintravitreal1.25 mg
Prescription Generics

false

International Brands

Jetrea

Synonyms

Manufacturers

Thrombo Genics Inc.

CAS number

1048016-09-6

UNII

7V6HE3DM5A

State

solid

Affected organisms

Humans and other mammals

Indication of Ocriplasmin

Ocriplasmin is a proteolytic enzyme indicated for the treatment for symptomatic vitreomacular adhesion.

Toxicity of Ocriplasmin

The most commonly reported reactions ( 5%) in patients treated with ocriplasmin were vitreous floaters, conjunctival hemorrhage, eye pain, photopsia, blurred vision, macular hole, reduced visual acuity, visual impairment, and retinal edema.

RX24 Drugs Disclaimer: before buying a Ocriplasmin on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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