Save up -80% on Octreotide
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Sandostatin
|$32.6||1 vial (5ml) 200mcg/ml|
|Price with discount in nearest pharmacy. Price may vary.|
We offer free Octreotide coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Octreotide every time. What are you waiting for? Claim your prescription drug card now!
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Octreotide volume of distribution
Octreotide acetate is administered parenterally; the immediate-release formulation should be given intravenously or subcutaneously, while the depot formulation should only be given intramuscularly. Approximately 65% of a dose is bound to lipoprotein and albumin in a concentration-dependent manner. The volume of distribution is estimated to be 13.6 L in adult patients. Octreotide undergoes extensive hepatic metabolism. Total body clearance ranges from 7—10 L/hour in adult patients. The apparent elimination half-life of immediate-release octreotide injection is 1.7—1.9 hours, which is significantly greater than somatostatin’s half-life of 1—3 minutes. Approximately 32% of a dose is excreted in the urine as unchanged drug.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Octreotide
Octreotide is the acetate salt of a cyclic octapeptide. It is a long-acting octapeptide with pharmacologic properties mimicking those of the natural hormone somatostatin.
Octreotide mechanism of action
Octreotide binds to somatostatin receptors. These receptors are coupled via pertussis toxin sensitive G proteins which lead to inhibition of adenylyl cyclase. Octreotide binding to these receptors also stimulates phosphotyrosine phosphatase and activation of the Na(+)/H(+) exchanger via pertussis toxin insensitive G proteins.
Dosage forms of Octreotide
|Injection||intravenous; subcutaneous||100 ug/mL|
|Injection||intravenous; subcutaneous||1000 ug/mL|
|Injection||intravenous; subcutaneous||200 ug/mL|
Pendopharm Division Of De Pharmascience Inc
Humans and other mammals
Indication of Octreotide
For treatment of acromegaly and reduction of side effects from cancer chemotherapy
Toxicity of Octreotide
Disseminated neuroendocrine tumours are difficult to treat and are generally not responsive to radiotherapy or chemotherapy. Nuclear medicine techniques using a radiolabelled somatostatin analogue. Octreotide, have been used for the diagnosis of neuroendocrine tumours. It has been suggested that high activities of such an agent may have a therapeutic effect. The aims of this study were to assess toxicity and to determine if there had been evidence of efficacy.
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