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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Ofloxacin

Apo-Ofloxacin 0.3 % Solution

$1.04

ml

* price without discount in nearest pharmacy. Price may vary.

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Ofloxacin volume of distribution

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What is Ofloxacin

A synthetic fluoroquinolone (fluoroquinolones) antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Ofloxacin mechanism of action

Ofloxacin acts on DNA gyrase and toposiomerase IV, enzymes which, like human topoisomerase, prevents the excessive supercoiling of DNA during replication or transcription. By inhibiting their function, the drug thereby inhibits normal cell division.

Dosage forms of Ofloxacin

FormRouteStrength
Liquidintravenous20 mg
Tabletoral200 mg
Tabletoral300 mg
Prescription Generics

true

International Brands

Apo-ofloxacin

Synonyms

8-Fluoro-3-methyl-9-(4-methyl-piperazin-1-yl)-6-oxo-2,3-dihydro-6H-1-oxa-3a-aza-phenalene-5-carboxylic acid Ofloxacine

Manufacturers

Apotex Inc

CAS number

82419-36-1

UNII

A4P49JAZ9H

State

solid

Affected organisms

Enteric bacteria and other eubacteria

Indication of Ofloxacin

For the treatment of infections (respiratory tract, kidney, skin, soft tissue, UTI), urethral and cervical gonorrhoea.

Toxicity of Ofloxacin

LD sub50 /sub=5450 mg/kg (orally in mice)

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