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Price of Olmesartan
Olmetec 20 mg Tablet
* price without discount in nearest pharmacy. Price may vary.
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Olmesartan volume of distribution
The volume of distribution is 17 L and olmesartan poorly crosses the blood brain barrier.
What is Olmesartan
Olmesartan is an antihypertensive agent, which belongs to the class of medications called angiotensin II receptor blockers. It is indicated for the treatment of high blood pressure and is marketed under the name Olmetec. The FDA label includes a black-box warning of injury and death to the fetus, so women of child-bearing age need to be warned and take the necessary precautions. Olmesartan is also contraindicated in diabetes mellitus patients taking aliskiren.
Olmesartan mechanism of action
Olmesartan is an ARB that selectively inhibits the binding of angiotensin II to AT1, which is found in many tissues such as vascular smooth muscle and the adrenal glands. This effectively inhibits the AT1-mediated vasoconstrictive and aldosterone-secreting effects of angiotensin II and results in a decrease in vascular resistance and blood pressure. Olmesartan is selective for AT1 and has a 12,500 times greater affinity for AT1 than the AT2 receptor. Also unlike the well-known ARB losartan, olmesartan does not have an active metabolite or possess uricosuric effects.
Dosage forms of Olmesartan
|Tablet, film coated||oral||20 mg/1|
|Tablet, film coated||oral||40 mg/1|
|Tablet, film coated||oral||5 mg/1|
Daiichi Sankyo, Inc.
Humans and other mammals
Indication of Olmesartan
For the treatment of hypertension.
Toxicity of Olmesartan
The main symptoms of overdose include low blood pressure and fast heartbeat.
Disclaimer: before buying a Olmesartan on prescription, consult your health care provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.